Results 21 to 30 of about 23,302 (264)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

On the origin of elasticity and heat conduction anisotropy of liquid crystal elastomers at gigahertz frequencies

Nature Communications, 2022
Elastic anisotropy of liquid crystals elastomers is typically measured at low frequencies for the applications such as soft robotics, actuators, and origami.
Yu Cang, Jiaqi Liu, Meguya Ryu, Bartlomiej Graczykowski, Junko Morikawa, Shu Yang, George Fytas   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Publisher Correction: Imaging spectroscopy of solar radio burst fine structures

Nature Communications, 2018
The original version of this article contained errors in Refs 15, 27, 32, 33 and 43, which were incorrectly given with the wrong journal name “Solid Phys.” rather than the correct “Sol. Phys.”.
E. P. Kontar, S. Yu, A. A. Kuznetsov, A. G. Emslie, B. Alcock, N. L. S. Jeffrey, V. N. Melnik, N. H. Bian, P. Subramanian   +8 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

First Detailed MeerKAT Imaging Spectroscopy of a Solar Flare

The Astrophysical Journal Letters
Radio observations provide powerful diagnostics of energy release, particle acceleration, and transport processes in solar flares. However, despite recent progress in radio interferometric imaging spectroscopy, current instruments still face limitations ...
Yingjie Luo, Eduard P. Kontar, Roelf Du Toit Strauss, Gert J. J. Botha, Tomasz Mrozek, Gelu M. Nita, Sarah Buchner, James O. Chibueze   +7 more
doaj   +1 more source

Quasi-thermal Noise Spectroscopy Analysis of Parker Solar Probe Data: Improved Electron Density Model for Solar Wind

The Astrophysical Journal, 2023
We present a comprehensive analysis of electron density measurements in the solar wind using quasi-thermal noise (QTN) spectroscopy applied to data from the first 15 encounters of the Parker Solar Probe mission (2018 November–2023 March). Our methodology
Oksana Kruparova, Vratislav Krupar, Adam Szabo, Marc Pulupa, Stuart D. Bale   +4 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Optimization of deposition parameters for thin film lithium phosphorus oxynitride (LIPON)

Eurasian Journal of Physics and Functional Materials, 2021
Thin film of lithium phosphorus oxynitride (LIPON) was successfully deposited by radio frequency (RF) magnetron sputtering technique using a Li3PO4 target.
B. .. Uzakbaiuly, A. .. Mukanova, I. .. Kurmabbayeva, Z. B. Bakenov   +3 more
doaj   +1 more source