Results 81 to 90 of about 4,915,463 (326)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Wideband Dual-Polarized Filtering Antennas Using Short-Circuited Coupling Structure for 4G/5G Multi-Input-Multi-Output (MIMO) Antenna Decoupling Design

open access: yesPhotonics
A short-circuited coupling structure (SCCS) is proposed to obtain a gain-filtering response for dual-polarized antennas. A conventional dipole is designed with two intrinsic radiation nulls.
Haitao Song, Feifei Zhang, Baoxing Duan
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Cooperative Spectrum Sensing in Cognitive Radio Networks: A Survey on Machine Learning-based Methods

open access: yesJournal of Telecommunications and Information Technology, 2020
The continuous growth of demand experienced by wireless networks creates a spectrum availability challenge. Cognitive radio (CR) is a promising solution capable of overcoming spectrum scarcity.
Sundous Khamayseh, Alaa Halawani
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Coexistence of 5G/6G and Digital Terrestrial Television Networks

open access: yesApplied Sciences
This paper analyzes practical solutions for implementing 5G/6G and Digital Terrestrial Television (DTT) network coexistence in the UHF band. Two potential scenarios are explored using the case study of a nationwide DTT network: spectrum splitting and ...
Dariusz Więcek   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Radio Spectrum Monitoring Using the DSA815 Spectrum Analyzer [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2023
This work aims to show how the data obtained from the DSA815 spectrum analyzer can be processed. For example, the monitoring of a frequency band 91.3MHz -109.2MHz was chosen, but other frequency bands within the measurement range of the analyzer (9Hz - 1.
MORGOȘ Florin Lucian   +3 more
doaj  

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