Results 91 to 100 of about 1,972,565 (234)

Clinical Impact of Target‐Mediated Drug Disposition of Small Molecules with Focus on Early Phase I Study Designs

Clinical Pharmacology &Therapeutics, EarlyView.
Francesca Tessaro, Neil John Parrott, Matthias B Wittwer, Franziska Schaedeli Stark, Andrés Olivares‐Morales, Michael Derks, Stefan Sturm   +6 more
wiley   +1 more source

Early Feasibility of Registration of Micro‐PET/CT Scans to Annotated 3D Specimen Models

Head &Neck, EarlyView.
ABSTRACT Background Intraoperative 18F‐fluorodeoxyglucose (18F‐FDG) micro‐positron emission tomography/computed tomography (micro‐PET/CT) is an emerging modality for margin assessment. Prior to clinical use, micro‐PET/CT margin distances must be correlated with gold‐standard histopathology.
Joaquin Austerlitz, Andreja Radevic, Ashtyn McAdoo, Kyrionna Golliday, Cheng Ye, Daniel Fabbri, Adam J. Rosenberg, Marcus Balanky, Anas Alabkaa, Kim A. Ely, Mitra Mehrad, Spencer Roark, Eben Rosenthal, Michael C. Topf   +13 more
wiley   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

Head &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent, Adrien Nguyen Quoc, Christine Lefevre, Laura González‐Briceño, Caroline Thalassinos, Isabelle Flechtner, Dulanjalee Kariyawasam, Yamina Dassa, Magali Viaud, Dinane Samara‐Boustani, Graziella Pinto, Hervé Monpeyssen, Sabine Sarnacki, Vincent Couloigner, Michel Polak, Athanasia Stoupa   +15 more
wiley   +1 more source

Surgery After Thermal Ablation of Thyroid Nodules: A Systematic Review of Surgical Risk, Strategy and Pathological Findings

Head &Neck, EarlyView.
ABSTRACT Background Thermal ablation is increasingly used for selected thyroid nodules, but some patients subsequently require thyroidectomy. The effect of prior ablation on surgical risk, operative strategy, and histopathology remains unclear. Methods PubMed/MEDLINE, EMBASE, and the Cochrane Library were searched from inception to May 2026 for studies
Francesco Brucchi, Federica Poli, Beatrice Sperotto, Carla Colombo, Laura Fugazzola, Gianlorenzo Dionigi   +5 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Remote Sensing for Irrigation Water Management—The State of the Art and Prospects for Near‐Future Operations

Irrigation and Drainage, EarlyView.
ABSTRACT A recent UN report describes many regions as facing ‘water bankruptcy,’ a condition in which available water resources can no longer meet existing demands. In practice, this means irrigation will likely bear the greatest burden of future water‐use reductions, a complicated and fraught decision to make given its critical role in food security ...
Wim G. M. Bastiaanssen, Chris Perry, Royce Dalby, Yasir Mohamed, Xueliang Cai, Poolad Karimi, IJsbrand de Jong, Pasquale Steduto, Marat Beksultanov, Christopher C. M. Neale, David Molden, Waqas Awan, Laarousi Mohamed, Jippe Hoogeveen, Jeff Davids, Nutchanart Sriwongsitanon, P. S. Rao, Roula Bachour, Palitha Bandara, Sophea Chhim, Richard Evans, Tom Lahad, D. Nagesh Kumar, Zakaria Adawy, Devendra Singh Bundela, Kawa Hakzi, Isaya Kisekka, Nicolas Puelma, Alejandro A. Pannunzio, Benjamin Koetz, Mukhiddin Ibragimov   +30 more
wiley   +1 more source

Cytotoxic and Oxidative Effects of Common Pesticides on Hepatic and Renal Cell Lines (HepG2 and Hek‐293): Implications for Human Health and Environmental Safety

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modern agricultural practices expose humans and the environment to numerous chemical pesticides. Increasing evidence suggests that commercial pesticide formulations may exhibit toxicological properties that differ from those of their active ingredients alone due to the presence of co‐formulants and additives. This study evaluated the cytotoxic
Fares Elghali, Kawther Bedchich, Nour Kacem, Mohamed Sami Aifa   +3 more
wiley   +1 more source

Radiation‐Related Knowledge and Attitudes Toward Medical Imaging Among the General Population in Iraq: A Cross‐Sectional Survey

Journal of Medical Radiation Sciences, EarlyView.
A cross‐sectional survey of 1274 adults residing in Iraq found a median radiation‐related knowledge score of 5/10 and a median attitude score of 17/25. Only 18% correctly identified that MRI does not use ionizing radiation, while 36% recognized that a spiral CT scan may involve radiation equivalent to 100–800 conventional X‐rays.
Walid Al‐Qerem, Aiham Assie Hammood, Alaa Hussein Alsajri, Anan Jarab, Judith Eberhardt, Lama Sawaftah   +5 more
wiley   +1 more source

Implementation of the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management [PDF]

, 2004
This paper discusses the implementation of the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management. The Joint Convention: establishes a commitment with respect to safe management of spent nuclear fuel
Stewart, L., Tonkay, D.
core  

Oncoplastic Surgery Versus Total Breast Reconstruction in Locally Advanced and Multicentric Carcinomas. A Matched Comparative Cohort Study of Oncologic and Aesthetic Outcomes

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background/Objective This study aimed to compare extreme oncoplastic surgery (EO‐partial breast reconstruction for tumors > 5 cm or multicentric lesions) with extreme reconstruction (ER‐mastectomy with reconstruction for tumors >5 cm or multicentric lesions).
Aline Regina Nunes‐Reis, Regis Resende Paulinelli, Rosemar Macedo Sousa Rahal, Luiz Fernando Jubé Ribeiro, Ruffo de Freitas Júnior   +4 more
wiley   +1 more source