Results 91 to 100 of about 67,308 (301)

Unexpected Victory: High-Risk Papillary Thyroid Cancer with Distant Metastases Shows Extraordinary Response to First RAI Treatment

open access: yesJournal of the Pakistan Medical Association
Papillary Thyroid Cancer (PTC) is the most prevalent type of differentiated thyroid cancer. Its incidence is growing worldwide although it has low death rates. Treatment includes surgery followed by radioactive iodine therapy.
Muntaha Fatima Rana   +2 more
doaj   +1 more source

Revisionist history uncovers a simplified molecular‐based classification of differentiated thyroid cancer

open access: yesThe Journal of Pathology, EarlyView.
Abstract The diagnostic classification of differentiated thyroid cancer has been a longstanding topic of debate among pathologists, largely due to high interobserver variability. This complexity has increased with the expansion of tumor types and subtypes.
Sylvia L Asa   +8 more
wiley   +1 more source

Removal of radioactive methyliodide from the gas stream with a composite sorbent based on polyurethane foam

open access: yesNuclear Engineering and Technology, 2020
A composite iodine sorbent was obtained in the form of porous polymer matrix with activated carbon particles impregnated with triethylenediamine deposited on its surface.
Alexander V. Obruchikov   +2 more
doaj  

Population Pharmacokinetics Modeling of Selpercatinib to Support Posology in Pediatric Patients With RET‐Altered Metastatic Thyroid Cancer or Solid Tumors

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Selpercatinib is a first‐in‐class, highly selective, RET kinase inhibitor with CNS activity, approved for the treatment of RET‐altered lung, thyroid, and other cancers. We report pharmacokinetic analyses to identify factors affecting selpercatinib steady‐state exposure and support posology in pediatric patients.
Dan Liu, Jan‐Stefan van der Walt
wiley   +1 more source

Rare Co-occurrence of Ocular Myasthenia Gravis and Thyroid-Associated Orbitopathy (Ophthalmopathy) in an Individual With Hypothyroidism

open access: yesFrontiers in Endocrinology, 2019
Ocular myasthenia gravis (Ocular MG, OMG) shares many clinical features with thyroid-associated orbitopathy or thyroid-associated ophthalmopathy (TAO). In the rare instance of their coexistence, clinicians may fail to diagnose ocular MG when TAO is also ...
Ran An   +5 more
doaj   +1 more source

Focal Spot, Spring 2008 [PDF]

open access: yes, 2008
https://digitalcommons.wustl.edu/focal_spot_archives/1108/thumbnail ...

core   +1 more source

State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna   +4 more
wiley   +1 more source

Tumor‐Targeted Radioiodinated Glyconanoparticles for Doxorubicin Delivery and Auger‐Chemotherapy in Triple‐Negative Breast Cancer

open access: yesSmall, EarlyView.
Combining multiple anti‐tumor therapeutic modalities using nanoparticles allows harnessing their therapeutic potential in combination with minimal side effects at lower doses. This study focuses on the development of tumor‐responsive core‐shell glyconanoparticle formulation targeting galectin‐3 in triple‐negative breast cancer (TNBC) for Auger ...
Shishu Kant Suman   +3 more
wiley   +1 more source

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