Results 91 to 100 of about 70,433 (233)

Neoadjuvant endocrine therapy often leads to breast and axilla‐conserving surgery in stages II and III hormone receptor‐positive breast cancer patients: A registry study

open access: yesInternational Journal of Cancer, Volume 158, Issue 7, Page 1905-1915, 1 April 2026.
What's new? This study evaluated patient characteristics and treatment strategies in stages II and III HR+/HER2− breast cancer. Neoadjuvant systemic therapy frequently facilitated breast‐conserving procedures and less invasive axillary surgery. Approximately half of the patients undergoing primary surgery received a mastectomy, and all with positive ...
Layla Andour   +5 more
wiley   +1 more source

Focal Spot, Spring 2008 [PDF]

open access: yes, 2008
https://digitalcommons.wustl.edu/focal_spot_archives/1108/thumbnail ...

core   +1 more source

Surgical Outcomes Following Neoadjuvant‐Targeted Therapy for Advanced Differentiated Thyroid Cancer—Real‐World Data

open access: yesClinical Endocrinology, Volume 104, Issue 3, Page 270-280, March 2026.
ABSTRACT Background Differentiated thyroid carcinoma (DTC) is typically managed surgically with favourable outcomes. However, surgery may have dire consequences when the tumour invades critical structures. Neoadjuvant therapy with tyrosine kinase inhibitors (TKIs) has emerged as a potential strategy to improve resectability and reduce morbidity in ...
Alexandra Dorman   +15 more
wiley   +1 more source

Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2‐nitroimidazole TAT Conjugate

open access: yesDrug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Mediated by their protein transduction domain, cell‐penetrating peptides (CPPs) have been widely explored for facilitating intracellular delivery of drugs and small molecules. In this study, a radiolabeled, 2‐nitroimidazole conjugated TAT (TAT ‐ transactivator of transcription) peptide was prepared and evaluated for targeting tumor hypoxia ...
Sweety Mittal   +4 more
wiley   +1 more source

Impact of repeated dose of stable iodine in an in utero rat model using a metabolomic approach

open access: yesBIO Web of Conferences, 2019
The Fukushima nuclear power plant blast resulted in the release of 131Iodine for several weeks. This unexpected issue challenged the iodin doctrine [1], in which the counter-measure is to provide a unique iodine tablet to saturate thyroid during the ...
Rosique Clément   +3 more
doaj   +1 more source

Partial Laryngectomy for Thyroid Cancer: A Single Institution Case Series With Operative Techniques

open access: yesHead &Neck, Volume 48, Issue 2, Page E20-E24, February 2026.
ABSTRACT Background Partial laryngectomy has been well described as a management option for T1–3 laryngeal squamous cell cancers. However, there are a few case reports of partial laryngeal surgery for locally advanced thyroid carcinoma. Methods This is a case series of five patients with thyroid carcinoma (one primary and four recurrent) with laryngeal
Ella E. Hawes   +17 more
wiley   +1 more source

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

open access: yesSmall, Volume 22, Issue 8, 6 February 2026.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad   +11 more
wiley   +1 more source

On-line Excited-State Laser Spectroscopy of Trapped Short-Lived Ra$^+$ Ions [PDF]

open access: yes, 2010
As an important step towards an atomic parity violation experiment in one single trapped Ra$^+$ ion, laser spectroscopy experiments were performed with on-line produced short-lived $^{212,213,214}$Ra$^+$ ions. The isotope shift of the $6\,^2$D$_{3/2}$\,-\
Berg, J. E. van den   +13 more
core   +2 more sources

Synthesis and Application of [18F]Togni Reagent I: An Electrophilic 18F‐Labeled Trifluoromethylating Reagent for Positron Emission Tomography Tracer Synthesis

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 4, January 26, 2026.
Togni reagent I, one of the most used electrophilic trifluoromethylating reagents, has been radiolabeled with fluorine‐18 starting from the widely available fluoro‐benziodoxole and the [18F]Ruppert–Prakash reagent. To demonstrate the broad potential for late‐stage functionalization, aliphatic carboxylic acids were successfully converted into their 18F ...
Lizeth Y. F. Haveman   +2 more
wiley   +1 more source

Unexpected Victory: High-Risk Papillary Thyroid Cancer with Distant Metastases Shows Extraordinary Response to First RAI Treatment

open access: yesJournal of the Pakistan Medical Association
Papillary Thyroid Cancer (PTC) is the most prevalent type of differentiated thyroid cancer. Its incidence is growing worldwide although it has low death rates. Treatment includes surgery followed by radioactive iodine therapy.
Muntaha Fatima Rana   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy