Results 111 to 120 of about 67,308 (301)

Circadian Gene BMAL1 Regulation of Cellular Senescence in Thyroid Aging

open access: yesAging Cell, EarlyView.
BMAL1 downregulation during aging reduces NFKBIA expression, accelerating thyroid cellular senescence and impairing hormone synthesis. Circadian rhythm disruption exacerbates thyroid functional decline, highlighting the BMAL1‐NFKBIA axis as a key mediator of aging‐related thyroid dysfunction and offering insights for stabilizing thyroid health in aging
Dandan Zong   +4 more
wiley   +1 more source

216 Jewish Hospital of St. Louis [PDF]

open access: yes, 1953
https://digitalcommons.wustl.edu/bjc_216/1009/thumbnail ...

core   +1 more source

CD105 (Endoglin) Expression as a Prognostic Marker in Aggressive Papillary Thyroid Carcinoma

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Background Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy, with a generally favourable prognosis. However, a subset of PTC cases exhibit aggressive behaviour, including lymph node and distant organ metastases. Identifying biomarkers that can differentiate between benign and malignant lesions, as well as predict
İlker Çordan, Tuğba Günler
wiley   +1 more source

Tracheal nodularity and paratracheal soft tissue nodule: post-radioactive iodine treatment changes with peculiar visual and pathologic findings in a case of metastatic follicular variant papillary thyroid carcinoma: a case report

open access: yesJournal of Medical Case Reports
Background Follicular variant papillary thyroid carcinoma is a distinct subtype of papillary thyroid carcinoma that can occasionally present with aggressive features, including distant metastases and extrathyroidal extension.
Benjamin L. Sievers   +8 more
doaj   +1 more source

Clues in the rare gas isotopes to early solar system history [PDF]

open access: yes
The results of the radioactive dating and the discovery of gas-rich meteorites on the Moon surface are reviewed. Special attention is paid to the extinct radioactivity iodine-129.
Reynolds, J. H.
core   +1 more source

Ten Year Outcome of Anti‐Thyroid Drug Treatment for First Episode Graves' Thyrotoxicosis: The Predictive Importance of TRAb

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To establish the risk and time course of recurrent thyrotoxicosis following withdrawal of anti‐thyroid drugs (ATD) and risk factors for recurrence. Design Single‐centre retrospective study. Methods Two hundred and ninety people with a first episode of Graves' thyrotoxicosis, who completed a course of ATD, were included.
Nyo Nyo Z. Tun   +4 more
wiley   +1 more source

Volume kinetics of lactated Ringer's solution in adult horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Fluid therapy in horses is primarily empirical. Evidence‐based quantification of the disposition of intravenous (IV) crystalloids used in clinical practice could enhance the effectiveness of fluid therapy. Objectives To determine the pharmacokinetics (i.e., volume kinetics: VK) and associated haemodynamic effects of IV lactated ...
William W. Muir   +3 more
wiley   +1 more source

Impact of Different Modalities of Radiotherapy in Locally Advanced Pancreatic Cancer: A Review and Meta‐Analysis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a high‐mortality cancer in dire need of more effective therapeutic strategies. Six randomized controlled trials have compared chemotherapy with chemoradiotherapy in patients with locally advanced pancreatic cancer (LAPC), but these trials only involved conventional external beam radiotherapy ...
Amanda H. Lim   +6 more
wiley   +1 more source

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