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Radioactive iodine therapy

Current Opinion in Endocrinology, Diabetes & Obesity, 2012
Review of the management decisions that must be made by the endocrinologist during the use of radioactive iodine (RAI) therapy of hyperthyroidism and differentiated thyroid cancer.Since the 1940s radioactive (131)I (RAI) therapy has been a major component of the treatment of hyperthyroidism and differentiated thyroid cancer.
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Radioactive Iodine: A Living History

Thyroid®, 2023
Background: Before the development of antithyroid drugs in the 1940s, treatment of Graves' hyperthyroidism was primarily surgical. Surgical mortality was quite variable, but a significant minority of patients died during or after surgery. Summary: In 1936, Karl Compton, President of the Massachusetts Institute of Technology, in a lecture attended by ...
Gilbert H, Daniels, Douglas S, Ross
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The Destructive Effects of Radioactive Iodine

The British Journal of Radiology, 1955
The therapeutic use of 131I is based upon the ability of thyroid and thyroid-like tumour tissue to concentrate and store iodine in amounts greatly in excess of other tissues in the body. Cell destruction is caused mainly by the ionizing effects of β particles whose range is short so that the destructive effects are localised. This paper deals with some
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Radioactive Iodine Therapy

2011
Radioactive iodine (RAI; I-131) has been used to destroy thyroid ­carcinoma tissue postoperatively in patients with and without known residual disease since the mid-twentieth century. By eliminating remaining normal thyroid tissue, RAI ablation facilitates monitoring for persistent or recurrent thyroid carcinoma with thyroglobulin levels and iodine ...
Alan D. Waxman, Wendy Sacks
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THE TREATMENT OF HYPERTHYROIDISM WITH RADIOACTIVE IODINE

Journal of the American Medical Association, 1946
Roentgen treatment has been used for hyperthyroidism for many years. In 1923 Means and Holmes 1 pointed out that in this form of treatment about one third of the patients are cured, another third improved and another third not affected. Since 1923 ordinary iodine by mouth has been used as a preoperative method of quieting the hyperactive thyroid in ...
Robley D. Evans, Earle M. Chapman
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THE UPTAKE OF RADIOACTIVE IODINE BY ASCOPHYLLUM

The Biological Bulletin, 1951
During the course of experiments designed to determine the relation between respiration and iodine uptake in brown algae (to be published elsewhere), it was observed that the uptake of radioactive iodine followed over a period of 15-20 hours gave a definite pattern of behavior.
Sally Kelly, Norman A. Baily
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Induction of hyperparathyroidism by radioactive iodine

The American Journal of Surgery, 1984
External irradiation to the head and neck has been associated with the emergence of hyperparathyroidism, due both to adenoma and hyperplasia since a single case report was published in 1975. A recent report indicates that there may be some association between hyperparathyroidism and radioiodine administered for thyroid disease.
Irving B. Rosen   +3 more
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Cardiotoxic Thyroid and Radioactive Iodine

JAMA, 1960
A study was made of 43 patients with heart disease who could not be restored to a comfortable state of ambulation by treatment with digitalis, diuretics, low-sodium diet, and other medication. In this group there were 5 men and 20 women with definite evidence of thyroid abnormalities.
Henrietta S. Hayden   +2 more
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TREATMENT OF HYPERTHYROIDISM WITH RADIOACTIVE IODINE

Endocrinology and Metabolism Clinics of North America, 1998
Treatment of hyperthyroidism with RAI has been performed for more than a half century with efficacy and safety. For its optimal use, the physician must employ appropriate patient selection criteria and clinical judgment concerning pretreatment patient preparation.
Donald A. Meier   +2 more
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RADIOACTIVE IODINE IN THE STUDY OF THYROID PHYSIOLOGY

Journal of the American Medical Association, 1946
In previously published experiments of this series 1 radioactive iodine was used as an indicator in the study of animal and human thyroid physiology and iodine metabolism. Much of this preliminary work was done with a view to the discovery of the conditions under which radioactive iodine might be administered with maximum radiational effect in the ...
Arthur Roberts, Saul Hertz
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