Results 111 to 120 of about 42,153 (259)

Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene

open access: yesDrug Testing and Analysis, EarlyView.
Eight metabolites for N‐pyrrolidino fluetonitazene were identified in vitro, three of which (M2, M6 and M8) were present in an authentic urine sample. M2 was the most abundant in vivo metabolite and is a common marker metabolite of nitazepyne‐type substances.
Severin Zemp   +6 more
wiley   +1 more source

The damage and failure mechanism of prestatically loaded rock during medium‐strain rate cyclic impact loading

open access: yesDeep Underground Science and Engineering, EarlyView.
Based on experimental results and theoretical analysis, an established rock damage accumulation model that comprehensively considers the preapplied static load, impact peak value, impact frequency, and impact times. Abstract To study the rock damage mechanism under high static loading and superimposed medium strain rate cyclic impact loading, a series ...
Wei Wang   +6 more
wiley   +1 more source

A rock brittleness index based on the postpeak energy release rate and damage surface characteristics for brittle hard rock

open access: yesDeep Underground Science and Engineering, EarlyView.
This study examines energy evolution in rock rupture via triaxial direct shear tests, exploring the impact of confining pressure and temperature on fracture surface randomness. A novel energy‐based brittleness index is proposed, validated experimentally, and compared with existing methods for reliability and accuracy.
Biao Wang   +5 more
wiley   +1 more source

Thermal‐induced fracture evolution and acoustic signature of Beishan granite: Insights into tensile strength of barrier system for high‐level radioactive waste disposal

open access: yesDeep Underground Science and Engineering, EarlyView.
The tensile strength of granite, a proposed host for nuclear waste, degrades severely above 400°C. We link this to specific microcracking patterns captured by acoustic emission, establishing a scientific basis for assessing repository safety under thermal load.
Wei Zeng   +7 more
wiley   +1 more source

A Thermally Robust Luminescent Antimony Halide for Real‐Time Detection of Volatile Iodine at Elevated Temperatures

open access: yesEcoEnergy, EarlyView.
Zero‐dimensional antimony halides drive efficient iodine capture through electron transfer and display rapid fluorescence quenching at 75°C (348 K), establishing the first luminescent sensor for real‐time I2 detection at elevated temperatures. ABSTRACT Real‐time monitoring of volatile molecular iodine (I2), a hazardous radioactive byproduct of nuclear ...
Ying Jiang   +13 more
wiley   +1 more source

Phosphate and fluoride removal options for Hanford high‐level waste sludge processing

open access: yesEnvironmental Progress &Sustainable Energy, EarlyView.
Abstract High‐phosphate and high‐fluoride sludges represent some of the most challenging waste streams within the Hanford High‐Level Waste (HLW) inventory due to solubility constraints, impacts on glass loading, and corrosion risks during vitrification.
A. M. Westesen   +4 more
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

open access: yesEpilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer   +7 more
wiley   +1 more source

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