Results 161 to 170 of about 42,153 (259)

Sodium Ions Affect GPR17 Conformational States and Functionality

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo, Simona Daniele, Davide Bianchi, Lara Russo, Stefano Capaldi, Maria Letizia Trincavelli, Ivano Eberini   +6 more
wiley   +1 more source

Advanced Nuclear Energy Pathways for a Net-Zero World: Fuel Cycles, Reactors, and Policy Readiness. [PDF]

Glob Chall
Haggam RA, Jayabal R, S S, Ayyar M, Soudagar MEM, M S, Rajendran S, D S, Sivanraju R.   +8 more
europepmc   +1 more source

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet, Klas Petersson, Marc C. Huisman, C. Willemien Menke‐van der Houven van Oordt, Iris H. C. Miedema, Andrea Thiele, Ghazal Montaseri, Alejandro Pérez‐Pitarch, David Busse   +8 more
wiley   +1 more source

Photonuclear Population of ^229m,gTh in Th-Doped Crystals Toward Nuclear Clock Development. [PDF]

Adv Sci (Weinh)
Lan HY, Wu D, Wang MZ, Chen ZY, Lv JF, Xia YH, Wang ZN, Luo W, Xu XL, Yan XQ.   +9 more
europepmc   +1 more source

Scaling turbulence drives the general circulation

Quarterly Journal of the Royal Meteorological Society, EarlyView.
The NOAA Gulfstream SP4, which deployed the GPS dropsondes over the NE Pacific Ocean as part of the Winter Storms Project during the January–March periods of 2004, 2005 and 2006. Abstract Statistical multifractal analysis of airborne and dropsonde observations is used to show that persistence of velocity after molecular collisions breaks the continuous
Adrian F. Tuck
wiley   +1 more source

Efficient adsorption of Sr²⁺ from simulated high-level liquid waste by 4A zeolite. [PDF]

BMC Chem
Qin X, Guo X, Tao X, Gao C, Yan X, Yan W.   +5 more
europepmc   +1 more source

Dumpsite Seabed Characterization of the San Pedro Basin, CA, From Autonomous Vehicle Observations

Journal of Field Robotics, EarlyView.
ABSTRACT A wide‐area seabed survey was conducted using autonomous underwater vehicles (AUVs) in a known dumpsite off the coast of Southern California that has been found to have widespread sediment contamination from the chemical dichlorodiphenyltrichloroethane (DDT).
Ryan A. McCarthy, Dylan Kriegman, Sophia T. Merrifield, Heidi Batchelor, Eric J. Terrill   +4 more
wiley   +1 more source

Bifunctional epoxy coatings containing new nano-hybrid based on lignin for decoration and gamma radiation shielding. [PDF]

Sci Rep
Zaher KSA, El-Gawad WMA, Ramadan W, Nawwar GAM.   +3 more
europepmc   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

Small, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom, Jae Hun Ahn, Jung Yung Kim, Kyo Chul Lee, Yong Jin Lee, Sanoj Rejinold N, Jin‐Ho Choy   +6 more
wiley   +1 more source

Porous Organic Polymers: From Molecular Design to Scalable Technologies

Small, EarlyView.
This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem, Hadi Shayesteh, Simindokht Zarei‐Shokat, Rokhsareh Bakhtiari, Sheyda Abedi‐Banaei, Zahra Sheikhlouiharzand, Parnia Mohebimanesh, Seyed Mohammad Amin Ojagh, Bahareh Bakhtiari, Ali Maleki, Theo G. M. van de Ven, Sohrab Zendehboudi, Ali Elkamel   +12 more
wiley   +1 more source