Results 91 to 100 of about 31,045 (299)

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg   +3 more
wiley   +1 more source

An experimental investigation on the safety performance of dry ice blasting technology

open access: yesNuclear Engineering and Technology
Dry ice blasting, a decontamination method with no secondary waste, is widely used in industry. Its safety is crucial in nuclear power plants. In this study, we carried out dry ice blasting treatment on five materials commonly used in nuclear power ...
Shulong Huang   +6 more
doaj   +1 more source

Using the criminal law to protect the environment: Possibilities and problems

open access: yesPeople and Nature, EarlyView.
Abstract Global biodiversity has declined rapidly in recent decades, and existing laws have proven insufficient to protect the environment from harm. There is no ‘silver bullet’ to remedying species population declines and extinctions and loss of ecosystems, but criminal law could be a crucial tool.
Kellie Toole   +5 more
wiley   +1 more source

Azole antifungal contaminants disrupt mycorrhizal function and risk agricultural sustainability

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Global food production is increasingly threatened by soil degradation, climate change and the rising costs of synthetic fertilisers. Circular agriculture, which promotes resource reuse, is a promising solution, but using treated wastewater and biosolids in farming introduces risks from emerging contaminants like pharmaceutical residues.
Emily K. Durant   +5 more
wiley   +1 more source

Elemental Geochemistry on Paleoenvironment Reconstruction: Proxies on Miocene-Pliocene of Marine to Fluvial Sediment in Serpong, Banten, Indonesia

open access: yesGeosciences
Research of the depositional environment using geological mapping, petrography, gamma-ray (GR) log, palynology, and foraminifera fossils of the Bojongmanik Formation has led to the formation of several different conclusions about the transition to the ...
Heri Syaeful   +14 more
doaj   +1 more source

State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna   +4 more
wiley   +1 more source

Neutron resonance absorption imaging of simulated high-level radioactive waste in borosilicate glass. [PDF]

open access: yesSci Rep, 2023
Oba Y   +7 more
europepmc   +1 more source

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