Results 201 to 210 of about 398,650 (328)

Microtracer-Based Assessment of the Mass Balance, Pharmacokinetics, and Excretion of [<sup>14</sup>C]Berzosertib, an Intravenous ATR Inhibitor, in Patients With Advanced Solid Tumors: A Phase 1 Study. [PDF]

open access: yesClin Pharmacol Drug Dev
Bolleddula J   +12 more
europepmc   +1 more source

Disposition and Absolute Bioavailability of Oral Imlunestrant in Healthy Women: A Phase 1, Open‐Label Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Imlunestrant (LY3484356) is a next‐generation orally bioavailable selective estrogen receptor degrader being investigated for the treatment of estrogen receptor–positive advanced breast and endometrial cancers. This Phase 1, open‐label, 2‐part study evaluated the disposition and absolute bioavailability of [14C]‐imlunestrant in 16 US‐based ...
Amita Datta‐Mannan   +6 more
wiley   +1 more source

Pharmacokinetic and Bioequivalence Evaluation of Two Sitagliptin Tablets With Different Salts in Healthy Subjects

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract The objective of the current study was to evaluate the rate and extent of absorption of a test formulation (sitagliptin hydrochloride) and a reference formulation (sitagliptin phosphate). An open‐label, randomized, single‐dose, single‐center, 2‐sequence, 2‐period, and cross‐over phase 1 study was implemented to assess the pharmacokinetic ...
Usok Hyun   +7 more
wiley   +1 more source

Rapid cleavage of 6-[<sup>18</sup>F]fluoronicotinic acid prosthetic group governs BT12 glioblastoma xenograft uptake: implications for radiolabeling design of biomolecules. [PDF]

open access: yesEJNMMI Radiopharm Chem
Dillemuth P   +15 more
europepmc   +1 more source

Radioactivity Applied to Chemistry

open access: green, 1951
Arthur C. Wahl, Norman A. Bonner
openalex   +2 more sources

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