Results 201 to 210 of about 257,139 (292)

Protecting CEACAM1 Expression Prevents Diet‐Induced Metabolic Dysfunction and Hepatic Fibrosis in Male Mice

Obesity, EarlyView.
ABSTRACT Objective High‐fat diet represses Ceacam1 transcription via a PPARα‐mediated mechanism to cause insulin resistance before inflammation develops. The current study investigated whether mutating PPRE‐RXRα in Ceacam1 promoter prevents diet‐induced metabolic abnormalities and hepatic fibrosis in male C57BL6/J mice.
Raziyeh Abdolahipour, Saja S. Khuder, William M. Philbrick, Agnes O. Portuphy, Getachew D. Belew, Hatem G. Fallouh, Harrison T. Muturi, Boyeon Kim, Jason K. Kim, Sonia M. Najjar   +9 more
wiley   +1 more source

A phase I dose-escalation/expansion study of fractionated-dose and multiple cycle anti-PSMA-targeted alpha emitter 225Ac-J591 in patients with prostate cancer. [PDF]

Clin Cancer Res
Tagawa ST, Thomas C, Arham AB, Holmes A, Marulanda Corzo V, Okobi T, Vallabhajosula S, Avlonitis V, Huicochea Castellanos S, Nauseef JT, O'Dwyer E, Fatima M, Gregos P, Yuan S, Sternberg CN, Molina A, Nanus DM, Bander NH, Osborne J.   +18 more
europepmc   +1 more source

2025 American Thyroid Association Management Guidelines for Adult Patients With Differentiated Thyroid Cancer: What's New for Surgeons?

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract The American Thyroid Association (ATA) has published an update to the 2015 management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer (DTC). This updated version focuses solely on the management of differentiated thyroid cancer, offering a comprehensive set of guidelines for all stakeholders in the care of ...
Chau Nguyen, Amanda Silver Karcioglu, Joseph Scharpf   +2 more
wiley   +1 more source

A Phase 1 Microtracer Study Evaluating the Mass Balance, Excretion, and Pharmacokinetics of Osivelotor in Healthy Participants. [PDF]

Clin Transl Sci
Zimmerman EI, Callegari E, Sharma R, Adenola A, Volpe J, Seetharaman K, Zhang C, Duchin K, Walker GS.   +8 more
europepmc   +1 more source

Clinical Effectiveness of Sialendoscopy in Radioactive Iodine‐induced Sialadenitis: A Systematic Review and Meta‐analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To systematically review and synthesize outcomes following sialendoscopy in patients with salivary gland dysfunction and a history of radioactive iodine (RAI). Data Sources A comprehensive search of Medline, Embase, and Cochrane Library was conducted from database inception through December 26, 2025.
Michal Kulasek, Alexander C. Moise, Sam J. Daniel   +2 more
wiley   +1 more source

Unravelling the human disposition of [¹⁴C]-vebreltinib: Faecal recovery of parent drug and a major circulating metabolite defines its mass balance profile. [PDF]

Br J Clin Pharmacol
Li L, Xue W, Yin H, Gao Q, Wu J, Shi H, Zhang P, Dong R.   +7 more
europepmc   +1 more source

Electrospun fibrous sorbents for the removal of uranium and americium from aqueous media

Polymer International, EarlyView.
Polymethacrylate‐based electrospun microfibers with tertiary amino functionalities are evaluated as adsorbents for U‐232 and Am‐241 in both simplified and complex (seawater) water matrices, highlighting their ability for efficient actinide removal. Abstract Polymethacrylate‐based electrospun microfibers containing tertiary amino functionalities were ...
Andreas Hadjianastasi, Ioannis Ioannidis, Petri C Papaphilippou, Ioannis Pashalidis, Theodora Krasia‐Christoforou   +4 more
wiley   +1 more source

Upregulation of Somatostatin Receptor Expression in Lactating Breast Shown in ^99mTc-HYNIC-TOC Scintigraphy. [PDF]

Diagnostics (Basel)
Jia M, Feng J, Luo Y.
europepmc   +1 more source

177Lu‐labeled amidoxime‐functionalized biodegradable microspheres for transarterial radioembolization of hepatocellular carcinoma

Precision Radiation Oncology, EarlyView.
Scheme 1. Schematic illustration of the synthesis and therapeutic evaluation of PLA‐g‐PAO microspheres (PLA‐g‐PAO‐Ms). Monodisperse PLA microspheres (PLA‐Ms) were initially fabricated via microfluidic technology. Surface grafting of acrylonitrile monomers was subsequently achieved through radiation‐induced graft polymerization, followed by ...
Xingliang Liu, Gang Wang, Zhenwen Zhao, Haoyu Wang, Hongyu Chen, Xiao Xu, Jingdong Li, Hongjuan Ma   +7 more
wiley   +1 more source