Results 231 to 240 of about 402,207 (326)

Rapid cleavage of 6-[¹⁸F]fluoronicotinic acid prosthetic group governs BT12 glioblastoma xenograft uptake: implications for radiolabeling design of biomolecules. [PDF]

EJNMMI Radiopharm Chem
Dillemuth P, Ayo A, Zhuang X, Lövdahl P, Liljenbäck H, Kärnä S, Auchynnikava T, Kunnas J, Ponkamo J, Miner MWG, Rajander J, Rosenholm JM, Roivainen A, Airaksinen AJ, Laakkonen P, Li XG.   +15 more
europepmc   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

Clinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou, Rohit Rao, Monica E. Shapiro, Nessy Tania, Cody Herron, Cynthia J. Musante, Jim H. Hughes   +6 more
wiley   +1 more source

Back-table specimen scanning using gantry-free hybrid hSPECT/LiDAR imaging: a feasibility study during PSMA-radioguided surgery. [PDF]

Surg Endosc
Pisano G, van Oosterom MN, Ottens VA, Berrens AC, Slof LJ, Çakal BA, Rietbergen DDD, van der Poel HG, van Leeuwen PJ, van Leeuwen FWB.   +9 more
europepmc   +1 more source

Statistical methods used in the measurement of radioactivity with some useful graphs and nomographs.

, 1946
A.A. Jarrett
openalex   +1 more source

Population Pharmacokinetics and Exposure–Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis

Clinical Pharmacology &Therapeutics, EarlyView.
Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich, Meenakshi Srinivasan, Yu Liu Ho, Sandra A.G. Visser, Geraldine Ferron‐Brady, Georgios Vlasakakis   +5 more
wiley   +1 more source

Management of radioiodine ablation therapy in haemodialysis patients with thyroid cancer: a case series of two patients. [PDF]

BMC Nephrol
Lin R, Malaroda AL, Ryder WJ, Wong VCK, Wong NL.   +4 more
europepmc   +1 more source

1,5‐Diisocyanonaphthalene: The Lowest Molecular Weight Fluorescent Probe for the Determination of Trace Amounts of Sulfoxides in Both Organic and Aqueous Media

ChemPhotoChem, EarlyView.
We present 1,5‐DIN as a low‐cost, efficient fluorescent probe for trace DMSO detection in organic and aqueous media. It shows strong quenching, with LODs from 5–50 ppm, even in complex matrices. Theoretical insights support its mechanism, highlighting its promise for practical applications.
Attila Kovács, Rajmond Schiwert, Péter Kun, Zoltán Mucsi, László Vanyorek, Béla Viskolcz, Miklós Nagy   +6 more
wiley   +1 more source

Radioactivity distribution and concomitant hazards evaluation of industrial zones soils from Chattogram, Bangladesh: A multivariate statistical analysis. [PDF]

PLoS One
Siraz MMM, Islam S, Shelley A, Alam MS, Mahmud A, Rashid MB, Khandaker MU, Yeasmin S, Rahman MS.   +8 more
europepmc   +1 more source

A continuous 500‐year sediment record of inundation by local and distant tsunamis in South‐Central Chile (40.1°S)

The Depositional Record, EarlyView.
Tsunami events over the past 500 years inundated Laguna Gemela West (Chile), leading to distinct sandy deposits in the lake record. This provides a complete perspective on tsunami inundation, including giant tsunamis, small local tsunamis and tsunamis that originated >100 km away from the site.
Jasper Moernaut, Evelien Boes, Daniel Melnick, Matías Carvajal, Markus Niederstätter, Sabine Schmidt, Diego Aedo, Mario Pino, Marc De Batist   +8 more
wiley   +1 more source

Syntheses and preclinical evaluations of ¹¹C-labeled radioligands for imaging brain orexin-1 and orexin-2 receptors with positron emission tomography. [PDF]

RSC Med Chem
Jana S, Ahmadi P, Yan X, Bai P, Liow JS, Jenson AE, Pamie-George MT, Zoghbi SS, Wu S, Wang C, Innis RB, Pike VW, Telu S.   +12 more
europepmc   +1 more source