Results 251 to 260 of about 402,207 (326)

The damage and failure mechanism of prestatically loaded rock during medium‐strain rate cyclic impact loading

open access: yesDeep Underground Science and Engineering, EarlyView.
Based on experimental results and theoretical analysis, an established rock damage accumulation model that comprehensively considers the preapplied static load, impact peak value, impact frequency, and impact times. Abstract To study the rock damage mechanism under high static loading and superimposed medium strain rate cyclic impact loading, a series ...
Wei Wang   +6 more
wiley   +1 more source

Engineering a Radiohybrid PSMA Ligand with an Albumin-Binding Moiety and Pharmacokinetic Modulation via an Albumin-Binding Competitor for Radiotheranostics. [PDF]

open access: yesMolecules
Hirata S   +9 more
europepmc   +1 more source

A rock brittleness index based on the postpeak energy release rate and damage surface characteristics for brittle hard rock

open access: yesDeep Underground Science and Engineering, EarlyView.
This study examines energy evolution in rock rupture via triaxial direct shear tests, exploring the impact of confining pressure and temperature on fracture surface randomness. A novel energy‐based brittleness index is proposed, validated experimentally, and compared with existing methods for reliability and accuracy.
Biao Wang   +5 more
wiley   +1 more source

Using ex vivo radioactivity measurement to differentiate parathyroid single-gland and multigland disease. [PDF]

open access: yesOncologist
Wang R   +8 more
europepmc   +1 more source

Re‐PERFUSE: Phase 1b study of AZD3427, a novel relaxin receptor agonist, on renal perfusion in HFrEF patients

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Renal impairment frequently coexists with heart failure (HF) and is associated with increased risk of poor clinical outcomes. This highlights the urgent need for therapies targeting both cardiac and renal dysfunction. AZD3427, a long‐acting recombinant fusion protein and relaxin analogue that selectively activates the relaxin family ...
Marcin Ufnal   +9 more
wiley   +1 more source

Seminars in epileptology: Presurgical epilepsy evaluation

open access: yesEpileptic Disorders, EarlyView.
Abstract All patients with drug‐resistant seizures benefit from a comprehensive evaluation to confirm their seizure diagnosis and explore surgical treatment options. This seminar in epileptology discusses advancements in the field and provides specific didactic material to create an active working knowledge for the care of patients with focal drug ...
Stephan Schuele   +11 more
wiley   +1 more source

Numerical Simulations of Hydraulic Fracturing in Carbonate‐Type Hot Dry Rock Reservoirs Based on the Coupled Thermo‐Hydraulic‐Mechanical‐Damage (THMD) Model

open access: yesEnergy Science &Engineering, EarlyView.
ABSTRACT Hydraulic fracturing technology is widely used in Enhanced Geothermal System (EGS) projects to induce fractures and enhance the permeability of thermal reservoirs. The hydraulic fracturing process of hot dry rock (HDR) is actually a multiphysics coupling process that couples the heat transfer field, seepage field, stress field, and damage ...
Zhiyu Tan   +4 more
wiley   +1 more source

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