Results 81 to 90 of about 383,199 (293)

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

Author Correction: Aerosol microphysics and chemistry reveal the COVID19 lockdown impact on urban air quality

Scientific Reports, 2021
Konstantinos Eleftheriadis, Maria I. Gini, Evangelia Diapouli, Stergios Vratolis, Vasiliki Vasilatou, Prodromos Fetfatzis, Manousos I. Manousakas   +6 more
doaj   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source

Optimal Configuration of Physical Process Parameterization Scheme Combination for Simulating Meteorological Variables in Weather Research and Forecasting Model: Based on Orthogonal Experimental Design and Comprehensive Evaluation Method

Atmosphere
The weather research and forecasting (WRF) model is frequently used to investigate the meteorological field around nuclear installations. The configuration of physical process parameterization schemes in the WRF model has a significant impact on the ...
Zhengming Li, Hanqing Wang, Xinyu Liu, Da Yuan   +3 more
doaj   +1 more source

Students' Beliefs About the Role of Atoms in Radioactive Decay and Half-life [PDF]

, 2007
Provides pedagogical insight concerning learners' pre-conceptions and misconceptions about radioactive decay The resource being annotated is: http://www.dlese.org/dds/catalog_ESA-000-000-000-035 ...
Lamont-Doherty Earth Observatory, Columbia University
core  

Synergistic Interplay of Acceptor and Isovalent Co‐Doping on BaZrO3‐Based Proton Conducting Oxides: A First‐Principles Study

Advanced Science, EarlyView.
Acceptor and isovalent co‐doping effects on hydration in BaZrO3 proton conductors are systematically investigated using first‐principles calculations. Acceptors enhance hydration by modulating oxygen vacancy formation, whereas isovalent dopants enhance hydration by stabilizing protons via increased A‐site cation–proton distances.
Yonghun Shin, Kyung‐Yeon Doh, June Ho Lee, Shin Hyun Kim, Donghwa Lee   +4 more
wiley   +1 more source

Two-year assessment of radon exposure in the underground tourist route in the Historic Silver Mine in Tarnowskie Góry (Poland)

Scientific Reports
This paper presents the results of a two-year radon risk study conducted at the Historic Silver Mine in Tarnowskie Góry. During this period, continuous measurements of radon activity concentration were carried out in three-month cycles at 30 points ...
Agata Grygier, Krystian Skubacz, Adam Piech, Jolanta Sobik-Szołtysek   +3 more
doaj   +1 more source

Training course for radiation safety technicians [PDF]

, 1967
Course of instruction includes sections on basic information, natural radioactivity, properties of alpha, beta, gamma, X rays, and neutrons, concepts of radiation units and dose determinations, shielding, biological effects, background radiation ...
Lasuk, S. R., Moe, H. J.
core   +1 more source