A Triangulenum‐Based Biosensor Platform for Mapping Kinase Activity in T Cells
Novel peptide biosensors based on long‐lifetime triangulenium dyes are developed for the real‐time, non‐invasive mapping of Akt1 and Src kinase activities in living cells. Utilizing FLIM microscopy, these highly specific, biocompatible probes overcome cellular autofluorescence.
Carmen Salto‐Giron +11 more
wiley +1 more source
Modification of the existing maximum residue levels for acequinocyl in celeries, Florence fennel and rhubarb. [PDF]
European Food Safety Authority (EFSA) +10 more
europepmc +1 more source
Mechanochemically Programmed, Oligomer‐Selective Amyloid Assembly via Axial Rotation
Tunable axial rotation mechanically redirects amyloid assembly without chemical additives. Low rotational speeds favor fibril maturation, whereas high‐speed rotation suppresses productive fibril amplification and biases the pathway toward oligomer‐enriched assemblies.
Seokbeom Roh +11 more
wiley +1 more source
Optimization of flushing strategies to minimize dilution of high-concentration radiopharmaceuticals in intravenous tubing. [PDF]
Li J +7 more
europepmc +1 more source
Competitive SELEX Strategy for High‐Affinity Aptamer Isolation and Enhanced Biosensing
A novel competitive SELEX strategy was developed to isolate high‐affinity aptamers by using a lower‐affinity competitor during the selection process. This approach enabled the identification of an aptamer with exceptional binding affinity, significantly improving target detection sensitivity.
Jiuxing Li +4 more
wiley +1 more source
Long-Term Variations in <sup>129</sup>I Seawater Concentrations off Fukushima and Potential of <sup>129</sup>I as an Oceanographic Tracer for ALPS-Treated Water. [PDF]
Suzuki T +5 more
europepmc +1 more source
Advances in research on layered double hydroxides for biomedical applications
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
Happy 95<sup>th</sup> birthday to Pierre Joliot, a brilliant scientist and a wonderful friend. [PDF]
Govindjee G, Bruce BD.
europepmc +1 more source
ABSTRACT Natural radionuclides in cement and gypsum production materials pose significant risks of occupational radiation exposure that are not well documented in Iraqi Kurdistan. This study quantifies alpha and gamma radiation levels from naturally occurring radioactive materials, specifically 222Rn, 238U, 232Th, and 40K, in cement and gypsum samples ...
Adil M. Hussien +4 more
wiley +1 more source
Healthcare Waste Toxicity: From Human Exposure to Toxic Mechanisms and Management Strategies. [PDF]
Cirstea I +4 more
europepmc +1 more source

