Results 31 to 40 of about 12,790 (299)

Monitoring of atmospheric emission of alpha emitters radionuclides at a nuclear fuel cycle facility in RJ, Brazil

open access: yesBrazilian Journal of Radiation Sciences, 2021
The Indústrias Nucleares do Brasil S/A (INB) in Resende, state of Rio de Janeiro, operate with open sources containing alpha emitters. This operation produces particulate material in the air.
Wagner De Souza Pereira   +5 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Elementary Analysis of Nail Polishes

open access: yesBrazilian Journal of Radiation Sciences, 2021
Brazil is considered the 4th largest CT&F Market in the world. In 2017,  the country earned R$ 102.5 billion, which means an increase of 3.2% over the year 2016. According to Associação Brasileira da Indústria de Higiene Pessoal, Perfumaria e Cosméticos (
Danielle Cristine Narloch   +3 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Optmization of exposure parameters in digital mammography (CR) using figure of merit

open access: yesBrazilian Journal of Radiation Sciences, 2021
A high diagnostic standard associated with the lowest radiation dose possible for the patient is the aim for a quality examination in mammography, this can be achieved through the Figure of Merit which is a parameter used for optimization in digital ...
Isabela Soares de Morais   +2 more
doaj   +1 more source

HELCOM-Monitoring of Radioactive Substances data - Germany (2021) [PDF]

open access: yes
Überwachungsdaten zu anthropogenen radioaktiven Stoffen Fisch-, Muschel-, Garnelen- und Wasserpflanzenproben. Empfohlene Zitierweise: Aust, M.-O., Nogueira, P., 2024. HELCOM-Monitoring of Radioactive Substances data - Germany (2021). HELCOM-Monitoring of
Aust, Marc-Oliver, Nogueira, P.
core   +1 more source

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li   +17 more
wiley   +1 more source

Ways to reduce radioactivity accumulation in the kidney during targeted therapy using small molecules, peptides and antibody fragments

open access: yesСибирский онкологический журнал
Administration of pharmaceuticals containing radioactive isotopes and capable of specific binding to certain proteins is one of the approaches used in the treatment or diagnosis of malignant tumors.
K. O. Avrov   +2 more
doaj   +1 more source

Effects of oxidatively modified LDL on cholesterol esterification in cultured macrophages.

open access: yesJournal of Lipid Research, 1990
Oxidative modification of low density lipoproteins (LDL) has been shown to cause accelerated degradation of LDL via the scavenger receptor pathway in cultured macrophages, and it has been proposed that this process might lead to cholesterol accumulation ...
HF Zhang, HJ Basra, UP Steinbrecher
doaj   +1 more source

Analysis of patients with prostate cancer care at a reference hospital in the state of Tocantins, suitable for brachytherapy

open access: yesBrazilian Journal of Radiation Sciences, 2021
A observação e identificação de fatores preditivos de resultados e morbidade são essenciais na seleção ideal de pacientes que podem usar a braquiterapia como modalidade de tratamento para o câncer de próstata.
André de Souza Bezerra   +2 more
doaj   +1 more source

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