Results 61 to 70 of about 21,334 (248)
Clinical Radiobiology of Fast Neutron Therapy: What Was Learnt?
Frontiers in Oncology, 2020 Neutron therapy was developed from neutron radiobiology experiments, and had identified a higher cell kill per unit dose and an accompanying reduction in oxygen dependency. But experts such as Hal Gray were sceptical about clinical applications, for good
B. Jones
semanticscholar +1 more source
Research Advances of the Autophagy‐Regulated Radiosensitivity
Cell Proliferation, EarlyView.Autophagy plays a dual role in regulating cellular radiosensitivity in radiotherapy (RT). We discuss the mechanisms by which autophagy promotes survival and growthsuppression by modulating radiosensitivity. It also outlines some frontier autophagy‐targeted radiotherapies. ABSTRACT Autophagy is an evolutionarily conserved process of cell self‐catabolism
Hanyue Liu +7 more
wiley +1 more source
Radiation biology - An important science for an advanced nuclear nation like South Africa
South African Journal of Science, 2012 The sustainability of radiation biology (radiobiology) is under threat in South Africa because of underdevelopment in the discipline, despite the fact that South Africa has been a user of radiation since radioactivity and X-rays were discovered.
Alistair Hunter
doaj
Seminars in nuclear medicine, 2020 As a treatment modality that is fundamentally different from other therapies against cancer, radiopharmaceutical therapy with alpha-particle emitters has drawn the attention of the therapy community and also the biopharmaceutical industry.
G. Sgouros
semanticscholar +1 more source
Treatment planning evolution: Comparing approaches in photodynamic and radiation therapies
Photochemistry and Photobiology, EarlyView.Oncological therapy based on radiation therapy (RT) is well‐developed, with widely accepted therapeutic dose concepts based on its mechanisms of action, which are applied to personalized treatment planning using sophisticated programs and tools.
Tina Saeidi +2 more
wiley +1 more source
Antibodies, 2012 Alpha-particle emitter labeled monoclonal antibodies are being actively developed for treatment of metastatic cancer due to the high linear energy transfer (LET) and the resulting greater biological efficacy of alpha-emitters.
Hong Song +3 more
doaj +1 more source
Radiobiology and treatment plan progress of FLASH radiotherapy
Fushe yanjiu yu fushe gongyi xuebao, 2023 FLASH radiotherapy is a novel method that has the potential to improve the therapeutic gain ratio to a new level. FLASH radiotherapy technology is mainly characterized by irradiation at ultra-high dose rate, which can reduce radiation-induced injury to ...
WU Xun +3 more
doaj +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Experimental Physiology, EarlyView.Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Life, 2023 Primary mucosal melanoma (PMM) and pancreatic ductal adenocarcinoma (PDAC) are two aggressive malignancies, characterized by intrinsic radio-chemoresistance and neurotropism, a histological feature resulting in frequent perineural invasion (PNI ...
Alexandra Charalampopoulou +10 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Long non‐coding RNAs (lncRNAs) KCNQ1OT1 and LINC‐PINT are upregulated in mouse, human and cell models of spaceflight‐induced muscle atrophy, revealing a novel regulatory role under (simulated) microgravity. Abstract Long non‐coding RNAs (lncRNAs) play an important role in the regulation of skeletal muscle transcriptional ...
Sergio Pérez‐Díaz +7 more
wiley +1 more source