Results 91 to 100 of about 26,902 (278)

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Synthesis and in vitro and in vivo evaluation of urea-based PSMA inhibitors with increased lipophilicity

EJNMMI Research, 2018
Background Several radiolabeled prostate-specific membrane antigen (PSMA) inhibitors based on the lysine-urea-glutamate (KuE) motif as the pharmacophore proved to be suitable tools for PET/SPECT imaging of the PSMA expression in prostate cancer patients.
Martina Wirtz, Alexander Schmidt, Margret Schottelius, Stephanie Robu, Thomas Günther, Markus Schwaiger, Hans-Jürgen Wester   +6 more
doaj   +1 more source

Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain

Pharmaceuticals, 2022
The degree of acetylation of lysine residues on histones influences the accessibility of DNA and, furthermore, the gene expression. Histone deacetylases (HDACs) are overexpressed in various tumour diseases, resulting in the interest in HDAC inhibitors ...
Oliver Clauß, Linda Schäker-Hübner, Barbara Wenzel, Magali Toussaint, Winnie Deuther-Conrad, Daniel Gündel, Rodrigo Teodoro, Sladjana Dukić-Stefanović, Friedrich-Alexander Ludwig, Klaus Kopka, Peter Brust, Finn K. Hansen, Matthias Scheunemann   +12 more
doaj   +1 more source

The Development and Challenges of PET/MRI Dual‐Modality Imaging Probes—An Update

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The integration of Positron emission tomography (PET) with Magnetic resonance imaging (MRI) combines the functional imaging capabilities of PET with the high‐resolution anatomical detail of MRI, creating a synergistic platform for advanced diagnostic imaging and image‐guided therapies. Central to the success of this dual‐modality system is the
Maryam Sabbaghan, Saumya Nigam, Isabella Kasabasic, Medha Manepalli, Ping Wang, Jinda Fan   +5 more
wiley   +1 more source

Recent Developments in Carbon-11 Chemistry and Applications for First-In-Human PET Studies

Molecules, 2023
Positron emission tomography (PET) is a molecular imaging technique that makes use of radiolabelled molecules for in vivo evaluation. Carbon-11 is a frequently used radionuclide for the labelling of small molecule PET tracers and can be incorporated into
Anna Pees, Melissa Chassé, Anton Lindberg, Neil Vasdev   +3 more
doaj   +1 more source

Development of novel fluorine-18 labeled PET radioligands for monoamine oxidase B (MAO-B) [PDF]

, 2013
Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selectiv e and irreversible MAO-B inhibitors such as L -deprenyl and rasagiline are clinically used for the t reatment of ...
Nag, Sangram
core   +2 more sources

Unleashing the Potential of Defect Engineered Persistent Pr3+‐Activated Phosphors for Multi‐Dimensional Anti‐Counterfeiting and X‐Ray Imaging Applications

Small, EarlyView.
Enhanced multicolor persistent luminescence with optimized trap depths (≈0.73 eV) in Ca3Ga2Ge3O12:Pr3+ phosphors enable advanced anti‐counterfeiting, optical storage, and high‐resolution X‐ray imaging (4 lp mm−1), surpassing commercial screens.
Annu Balhara, Santosh K. Gupta, Partha Sarathi Ghosh, Malini Abraham, Mohit Tyagi, Ashok Kumar Yadav, Subrata Das, Kathi Sudarshan, P. S. Sarkar   +8 more
wiley   +1 more source

Synthesis and Radiolabelling of DOTA-Linked Glutamine Analogues with 67,68Ga as Markers for Increased Glutamine Metabolism in Tumour Cells

Molecules, 2013
DOTA-linked glutamine analogues with a C6- alkyl and polyethyleneglycol (PEG) chain between the chelating group and the L-glutamine moiety were synthesised and labelled with 67,68Ga using established methods.
Ivan Greguric, Andrew G. Katsifis, Elisabeth Oehlke, Nigel A. Lengkeek, Nicholas R. Howell, Rachael K. Shepherd, Paul A. Pellegrini   +6 more
doaj   +1 more source

In Situ Impact of Waste Polyethylene (PE) Films on Soil Quality and Plant Growth in Agricultural Soil

Land Degradation &Development, Volume 36, Issue 14, Page 5054-5065, 30 August 2025.
ABSTRACT Plastic films have accumulated in soil ecosystems over decades of agricultural activities. These films potentially disrupt the soil structure, hinder nutrient cycling, and deteriorate soil quality. However, there is still a substantial knowledge gap in understanding how real‐world waste polyethylene films (WPEFs), with varied shapes and sizes,
Yoora Cho, Geonwook Hwang, Mee Kyung Sang, Patryk Oleszczuk, Jonathan Tian En Lee, Sung Yeon Hwang, Yong Sik Ok   +6 more
wiley   +1 more source

On the adsorption and reactivity of element 114, flerovium

Frontiers in Chemistry, 2022
Flerovium (Fl, element 114) is the heaviest element chemically studied so far. To date, its interaction with gold was investigated in two gas-solid chromatography experiments, which reported two different types of interaction, however, each based on the ...
A. Yakushev, A. Yakushev, L. Lens, L. Lens, Ch. E. Düllmann, Ch. E. Düllmann, Ch. E. Düllmann, J. Khuyagbaatar, J. Khuyagbaatar, E. Jäger, J. Krier, J. Runke, J. Runke, H. M. Albers, M. Asai, M. Block, M. Block, M. Block, J. Despotopulos, A. Di Nitto, A. Di Nitto, K. Eberhardt, U. Forsberg, P. Golubev, M. Götz, M. Götz, M. Götz, S. Götz, S. Götz, S. Götz, H. Haba, L. Harkness-Brennan, R.-D. Herzberg, F. P. Heßberger, F. P. Heßberger, D. Hinde, A. Hübner, D. Judson, B. Kindler, Y. Komori, J. Konki, J.V. Kratz, N. Kurz, M. Laatiaoui, M. Laatiaoui, M. Laatiaoui, S. Lahiri, B. Lommel, M. Maiti, A. K. Mistry, A. K. Mistry, Ch. Mokry, Ch. Mokry, K. J. Moody, Y. Nagame, J. P. Omtvedt, P. Papadakis, V. Pershina, D. Rudolph, L.G. Samiento, T.K. Sato, M. Schädel, P. Scharrer, P. Scharrer, P. Scharrer, B. Schausten, D. A. Shaughnessy, J. Steiner, P. Thörle-Pospiech, P. Thörle-Pospiech, A. Toyoshima, N. Trautmann, K. Tsukada, J. Uusitalo, K.-O. Voss, A. Ward, M. Wegrzecki, N. Wiehl, N. Wiehl, E. Williams, V. Yakusheva, V. Yakusheva   +81 more
doaj   +1 more source