Results 51 to 60 of about 10,349 (201)

Recent Developments in Carbon-11 Chemistry and Applications for First-In-Human PET Studies

Molecules, 2023
Positron emission tomography (PET) is a molecular imaging technique that makes use of radiolabelled molecules for in vivo evaluation. Carbon-11 is a frequently used radionuclide for the labelling of small molecule PET tracers and can be incorporated into
Anna Pees, Melissa Chassé, Anton Lindberg, Neil Vasdev   +3 more
doaj   +1 more source

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

Journal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel, Tse Wen Chang, Carmay Lim   +2 more
wiley   +1 more source

On the adsorption and reactivity of element 114, flerovium

Frontiers in Chemistry, 2022
Flerovium (Fl, element 114) is the heaviest element chemically studied so far. To date, its interaction with gold was investigated in two gas-solid chromatography experiments, which reported two different types of interaction, however, each based on the ...
A. Yakushev, A. Yakushev, L. Lens, L. Lens, Ch. E. Düllmann, Ch. E. Düllmann, Ch. E. Düllmann, J. Khuyagbaatar, J. Khuyagbaatar, E. Jäger, J. Krier, J. Runke, J. Runke, H. M. Albers, M. Asai, M. Block, M. Block, M. Block, J. Despotopulos, A. Di Nitto, A. Di Nitto, K. Eberhardt, U. Forsberg, P. Golubev, M. Götz, M. Götz, M. Götz, S. Götz, S. Götz, S. Götz, H. Haba, L. Harkness-Brennan, R.-D. Herzberg, F. P. Heßberger, F. P. Heßberger, D. Hinde, A. Hübner, D. Judson, B. Kindler, Y. Komori, J. Konki, J.V. Kratz, N. Kurz, M. Laatiaoui, M. Laatiaoui, M. Laatiaoui, S. Lahiri, B. Lommel, M. Maiti, A. K. Mistry, A. K. Mistry, Ch. Mokry, Ch. Mokry, K. J. Moody, Y. Nagame, J. P. Omtvedt, P. Papadakis, V. Pershina, D. Rudolph, L.G. Samiento, T.K. Sato, M. Schädel, P. Scharrer, P. Scharrer, P. Scharrer, B. Schausten, D. A. Shaughnessy, J. Steiner, P. Thörle-Pospiech, P. Thörle-Pospiech, A. Toyoshima, N. Trautmann, K. Tsukada, J. Uusitalo, K.-O. Voss, A. Ward, M. Wegrzecki, N. Wiehl, N. Wiehl, E. Williams, V. Yakusheva, V. Yakusheva   +81 more
doaj   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

Medicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg, Wolfgang A. G. Sauerwein, Evamarie Hey‐Hawkins   +2 more
wiley   +1 more source

One‐year follow‐up after fractionated ultra‐high‐dose‐rate FLASH radiotherapy in patient with extramammary Paget disease of the scrotum

Precision Radiation Oncology, EarlyView.
An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo, Chengliang Yang, Ronghu Mao, Leijie Ma, Hongchang Lei, Peng Chen, Yanping Zhang, Meng Xu, Chao Wang, Yiwu Wang, Mingxia Wu, Chanjun Sun, Han Liu, Hui Liu, Hong Ge   +14 more
wiley   +1 more source

Radiochemistry of uranium [PDF]

, 1962
This volume which deals with the radiochemistry of uranium is one of a series of monographs on radiochemistry of the elements. There is included a review of the nuclear and chemical features of particular interest to the radiochemist, a discussion of ...
Gindler, J.E.
core  

Quantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 826-838, August 2026.
ABSTRACT Purpose Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...
James A. Bankson, Joshua S. Niedzielski, Collin J. Harlan, Yunyun Chen, Christopher M. Walker, Philip L. Lorenzi, Lin Tan, Vikas Kundra, Matthew E. Merritt, Mukundan Ragavan, Dawid Schellingerhout, Renjie He, Yao Ding, Sahana Datar, Qing Wang, Christine B. Peterson, Clifton D. Fuller, Vlad C. Sandulache, Stephen Y. Lai   +18 more
wiley   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 7, Page 1300-1311, July 2026.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

WSB.APP/PS1 mice develop age‐dependent cerebral amyloid angiopathy, cerebrovascular dysfunction, and white matter deficits

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Cerebrovascular deficits, including cerebral amyloid angiopathy (CAA), play a key role in Alzheimer's disease (AD) pathogenesis. Here, we characterize the susceptibility of the WSB/EiJ genetic context to human AD‐relevant cerebrovascular phenotypes. METHODS CAA and parenchymal plaque analysis and in vivo neurovascular imaging were
Olivia J. Marola, Asli Uyar, Kelly J. Keezer, Juan Antonio K. Chong Chie, Kevin J. Elk, Abigail E. Cullen, Kierra Eldridge, Scott Persohn, Jonathan Nyandu Kanyinda, Jennifer D. Whitesell, Julie A. Harris, Paul Salama, Ashley E. Walker, Gregory W. Carter, Michael Sasner, Paul R. Territo, Gareth R. Howell, Kristen D. Onos   +17 more
wiley   +1 more source

A Robust Cost‐Effective Spectrophotometric Method for Nb Determination in Refractory Nb‐doped Gadolinium Zirconate: Overcoming Matrix Dissolution Challenges

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT A simple, robust and cost‐effective analytical methodology was developed for the determination of niobium in highly refractory materials: Nb‐doped gadolinium zirconate (Gd2Zr2O7:Nb) and niobium pentoxide (Nb2O5). The challenge of digesting these matrices was successfully accomplished by establishing two independent dissolution procedures: (i ...
Poonam Verma, Annapurna Chandane
wiley   +1 more source