Results 51 to 60 of about 22,957 (141)

Quantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...
James A. Bankson, Joshua S. Niedzielski, Collin J. Harlan, Yunyun Chen, Christopher M. Walker, Philip L. Lorenzi, Lin Tan, Vikas Kundra, Matthew E. Merritt, Mukundan Ragavan, Dawid Schellingerhout, Renjie He, Yao Ding, Sahana Datar, Qing Wang, Christine B. Peterson, Clifton D. Fuller, Vlad C. Sandulache, Stephen Y. Lai   +18 more
wiley   +1 more source

Geochemistry of cold seeps - Fluid sources and systematics [PDF]

, 2011
Emanation of fluids at cold seeps, mud volcanoes, and other types of submarine seepage structures is a typical phenomenon occurring at continental margins worldwide.
Haeckel, Matthias, Liebetrau, Volker, Romer, Rolf L., Schmidt, Mark, Wallmann, Klaus   +4 more
core  

One‐year follow‐up after fractionated ultra‐high‐dose‐rate FLASH radiotherapy in patient with extramammary Paget disease of the scrotum

Precision Radiation Oncology, EarlyView.
An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo, Chengliang Yang, Ronghu Mao, Leijie Ma, Hongchang Lei, Peng Chen, Yanping Zhang, Meng Xu, Chao Wang, Yiwu Wang, Mingxia Wu, Chanjun Sun, Han Liu, Hui Liu, Hong Ge   +14 more
wiley   +1 more source

Effective Preparation of [¹⁸F]Flumazenil Using Copper-Mediated Late-Stage Radiofluorination of a Stannyl Precursor

Molecules, 2022
(1) Background: [18F]Flumazenil 1 ([18F]FMZ) is an established positron emission tomography (PET) radiotracer for the imaging of the gamma-aminobutyric acid (GABA) receptor subtype, GABAA in the brain.
Mohammad B. Haskali, Peter D. Roselt, Terence J. O’Brien, Craig A. Hutton, Idrish Ali, Lucy Vivash, Bianca Jupp   +6 more
doaj   +1 more source

Influence of Peptide‐Based Chelator Sequences on HER2‐Targeting Radiopeptide

Journal of Peptide Science, Volume 32, Issue 5, May 2026.
Peptide‐based chelator consisting of Cys‐Gly‐Gly‐Gly incorporated into HER2‐targeting rL‐A9 peptide for 99mTc‐labeling. [99mTc]Tc‐CGGG‐rL‐A9 exhibited high binding affinity and tumor uptake and retention. ABSTRACT In our pursuit of developing HER2‐targeting radiolabeled peptides for detection and therapy of HER2‐positive breast cancer, the previously ...
Sonal Gupta, Manoj Kumar, Krishna Mohan Repaka, Amit Das, Ajit A. Kengar, Drishty Satpati   +5 more
wiley   +1 more source

Synthesis and in vitro and in vivo evaluation of urea-based PSMA inhibitors with increased lipophilicity

EJNMMI Research, 2018
Background Several radiolabeled prostate-specific membrane antigen (PSMA) inhibitors based on the lysine-urea-glutamate (KuE) motif as the pharmacophore proved to be suitable tools for PET/SPECT imaging of the PSMA expression in prostate cancer patients.
Martina Wirtz, Alexander Schmidt, Margret Schottelius, Stephanie Robu, Thomas Günther, Markus Schwaiger, Hans-Jürgen Wester   +6 more
doaj   +1 more source

Confining caesium in expanded natural Perlite [PDF]

, 2007
We present the potential use of expanded perlite, a metastable amorphous hydrated aluminum silicate, as a permanent medium for the long-term confinement of caesium.
Balencie, J., Boos, Anne, Burger, Didier, Estournès, Claude, Rehspringer, Jean Luc, Vilminot, Serge   +5 more
core   +6 more sources

Safety of [68Ga]Ga‐FAPI‐46 PET/CT including hemodynamic measurements and patient‐reported outcomes in cancer patients

Clinical Physiology and Functional Imaging, Volume 46, Issue 3, May 2026.
Abstract Introduction Aim Fibroblast activation protein inhibitor (FAPI) has demonstrated promising oncological diagnostic performance. Although no adverse events (AEs) have been previously reported, a formal safety evaluation of FAPI PET/CT is lacking.
Morten Bentestuen, Camilla Sylvest, Svend B. Jensen, Lara R. Soro, Aage Knudsen, Morten Ladekarl, Ole Thorlacius‐Ussing, Wolfgang P. Fendler, Helle D. Zacho   +8 more
wiley   +1 more source

Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain

Pharmaceuticals, 2022
The degree of acetylation of lysine residues on histones influences the accessibility of DNA and, furthermore, the gene expression. Histone deacetylases (HDACs) are overexpressed in various tumour diseases, resulting in the interest in HDAC inhibitors ...
Oliver Clauß, Linda Schäker-Hübner, Barbara Wenzel, Magali Toussaint, Winnie Deuther-Conrad, Daniel Gündel, Rodrigo Teodoro, Sladjana Dukić-Stefanović, Friedrich-Alexander Ludwig, Klaus Kopka, Peter Brust, Finn K. Hansen, Matthias Scheunemann   +12 more
doaj   +1 more source

Baryonium, a common ground for atomic and high energy physics [PDF]

, 2015
Indications of the existence of quasi-bound states in the N-Nbar system are presented. Measurements by BES discovered a broad enhancement close to the p-pbar threshold in the S wave, isospin 0 state formed in radiative decays of J/psi.
Dedonder, J. P., Loiseau, B., Wycech, S.
core   +2 more sources