Results 81 to 90 of about 12,648 (203)

Ultrasensitive Ion‐Imprinted Detection System with Pore‐Depended Electrochemiluminescence Mechanism for Accurate and Rapid Monitoring of Cesium in the Environment

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study focuses on the rapid and accurate determination of cesium, a key radioactive contaminant attracting global attention, by creating an ultrasensitive pore‐dependent electrochemiluminescence detection system. It has been successfully applied in the determination of various kinds of environmental samples, exhibiting its significance in the ...
Ziyu Wang, Lei Fang, Jianing Zhao, Chengqi Li, Hebing Xie, Jian‐Bin Pan, Daoben Hua   +6 more
wiley   +1 more source

Synthesis and in vitro and in vivo evaluation of urea-based PSMA inhibitors with increased lipophilicity

EJNMMI Research, 2018
Background Several radiolabeled prostate-specific membrane antigen (PSMA) inhibitors based on the lysine-urea-glutamate (KuE) motif as the pharmacophore proved to be suitable tools for PET/SPECT imaging of the PSMA expression in prostate cancer patients.
Martina Wirtz, Alexander Schmidt, Margret Schottelius, Stephanie Robu, Thomas Günther, Markus Schwaiger, Hans-Jürgen Wester   +6 more
doaj   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

ChemBioChem, Volume 27, Issue 1, January 2026.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh, Rupesh R. Kurhade, Abrar A. M. Siddiqui, Shaikh Shahbaz A. Majeed, Thomas J. Webster, Mohammad Intakhab Alam, Abdul Wasy Zia, Md. Faiyazuddin   +7 more
wiley   +1 more source

Liquid Chromatography‐Tandem Mass Spectrometry Methods for Rapid Measurement of the Molar Activity (Am) of Cyclotron‐Produced [18F]Fluoride and Derived Radiotracers

Chemistry–Methods, Volume 6, Issue 1, January 2026.
Accurate and simple liquid chromatography‐tandem mass spectrometry methods for measuring Am for [18F]fluoride on two rapidly derived surrogates, [18F]FAY and [18F]PCBSF, can serve as forensic tools for investigating the sources of carrier, Am determinations during routine tracer productions and be applied to radiotracers lacking a strong ultraviolet ...
Nicholas R. Ellin, Sean W. Costner, Cheryl L. Morse, Fatemak Ahmadi, Sanjay Telu, Fabrice G. Siméon, Shuiyu Lu, H. Umesha Shetty, Victor W. Pike   +8 more
wiley   +1 more source

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

Medicinal Research Reviews, Volume 46, Issue 1, Page 203-237, January 2026.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller, Nadia Bom Pedersen, Vladimir Shalgunov, Andreas Ingemann Jensen, Umberto Maria Battisti, Matthias Manfred Herth   +5 more
wiley   +1 more source

Methanobactin rapidly facilitates biliary copper excretion in a Wilson disease rat model visualised by 64Cu PET/MRI

British Journal of Pharmacology, Volume 183, Issue 2, Page 268-279, January 2026.
Background and Purpose Methanobactins are peptides with high copper affinity and potential to treat Wilson disease. We examined how two methanobactins (ARBM101 and MB‐OB3b) affected copper handling in the LPP Atp7b−/− Wilson disease rat model, compared to penicillamine or saline, by 64Cu positron emission tomography/magnetic resonance imaging ...
Emilie Munk Lynderup, Mikkel Holm Vendelbo, Frederik Teicher Kirk, Karina Højrup Vase, Aage Kristian Olsen Alstrup, Tamara Rieder, Alan A. DiSpirito, Jeremy D. Semrau, Tea Lund Laursen, Peter Ott, Hans Zischka, Thomas Damgaard Sandahl   +11 more
wiley   +1 more source

89Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art 89Zr Radiochemistry

Bioconjugate chemistry, 2017
Immuno-positron emission tomography (immunoPET) with 89Zr-labeled antibodies has shown great potential in cancer imaging. It can provide important information about the pharmacokinetics and tumor-targeting properties of monoclonal antibodies and may help
S. Heskamp, R. Raavé, O. Boerman, M. Rijpkema, Victor Goncalves, F. Denat   +5 more
semanticscholar   +1 more source

Determination of 55Fe and 63Ni in Pb–Bi by Radiochemical Separation Method

Science and Technology of Nuclear Installations, Volume 2026, Issue 1, 2026.
This paper introduces a simple and rapid separation method for the determination of 55Fe and 63Ni in lead–bismuth alloys. This method is based on chemical precipitation and solid‐phase extraction chromatography techniques, which can separate and purify individual radionuclides from sample matrix elements and other radionuclides.
Yaqing Ren, Yulong Du, Yufaning Yin, Xiaoyuan zhou, Ziliang Hou, Weinan Sun, Peng Lin, Kai Xu   +7 more
wiley   +1 more source

Late-Stage Copper-Catalyzed Radiofluorination of an Arylboronic Ester Derivative of Atorvastatin

Molecules, 2019
There is an unmet need for late-stage 18F-fluorination strategies to label molecules with a wide range of relevant functionalities to medicinal chemistry, in particular (hetero)arenes, aiming to obtain unique in vivo information on the pharmacokinetics ...
Gonçalo S. Clemente, Tryfon Zarganes-Tzitzikas, Alexander Dömling, Philip H. Elsinga   +3 more
doaj   +1 more source

Nuclear Data Needs for Radiochemistry

, 2021
A. Keksis, Donald Parsons, S.C. Frankle
openalex   +2 more sources