Results 31 to 40 of about 68,666 (258)

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Comparison of four radiofrequency ablation systems at two target volumes in an ex vivo bovine liver model [PDF]

, 2014
PURPOSEWe aimed to validate actually achieved macroscopic ablation volumes in relation to calculated target volumes using four different radiofrequency ablation (RFA) systems operated with default settings and protocols for 3 cm and 5 cm target volumes ...
Joern Rathke,, Bernd Hamm,, Ulf Teichgräber,, Hendrik Rathke,, Maximilian de Bucourt, Jens Rump,, Felix Güttler,   +6 more
core   +1 more source

Photonic Time Crystals and Time‐Varying Electromagnetic Metamatter: A New Direction for Ultrafast Tunable Photonic and Microwave Materials and Devices

Advanced Science, EarlyView.
Photonic time crystals (PTCs) are systems in which electromagnetic parameters are modulated periodically in time, producing momentum bandgaps via temporal scattering rather than spatial Bragg processes. This review examines the theoretical frameworks, modeling, and computational tools for time‐varying media, and summarizes experimental demonstrations ...
Ranjan Kumar Patel, Shriram Ramanathan, Ronald P. Jenkins, Michael J. Carter   +3 more
wiley   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source

Radiofrequency ablation of multiple accessory pathways

, 2002
The aim of the study was to review the clinical and electrophysiological characteristics and results of radiofrequency catheter ablation in patients with multiple accessory pathways to compare them with those of patients with single accessory pathways ...
Rodríguez-Chávez, Laura, Medeiros Domingo, Argelia, Colin, Luis, Iturralde, Pedro, Guevara-Valdivia, Milton   +4 more
core   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Rapid Fragment Screening by 19F Steady‐State Free Precession NMR

Angewandte Chemie, EarlyView.
19F$^{19}{\rm F}$ SSFP NMR is a broadband and very sensitive experiment for detecting protein–ligand interactions. The method enables rapid fragment screening at low micromolar protein concentrations, even for challenging drug targets such as intrinsically disordered proteins.
Laura Ruduša, Sintija Ozola, Kostiantyn P. Melnykov, Yaroslav I. Filatov, Serhiy V. Ryabukhin, Raitis Bobrovs, Dmytro M. Volochnyuk, Kristaps Jaudzems, Rihards Aleksis   +8 more
wiley   +2 more sources

A Randomized Trial Comparing Treatments for Varicose Veins [PDF]

, 2014
BACKGROUND: Ultrasound-guided foam sclerotherapy and endovenous laser ablation are widely used alternatives to surgery for the treatment of varicose veins, but their comparative effectiveness and safety remain uncertain. METHODS: In a randomized trial
Ramsay, Craig R, J Scott, Wileman, S., Elders, Andrew, Baker, Sara A., M Gough, G Scotland, Scott, Julian, Scotland, G., Gough, Michael, M K Campbell, E Tassie, J Norrie, S Baker, Burr, Jennifer, Campbell, Marion K, S Wileman, Campbell, Marion K., Burr, J., Bachoo, P., Ramsay, C. R., Lees, T., Baker, S. A., Earnshaw, J., Francis, J., Elders, A., Burr, J. M., Baker, S., S C Cotton, Brittenden, J., Campbell, Marion Kay, Norrie, John, Baker, Sara A, B Campbell, Francis, Jill, J Francis, Tassie, Emma, Scott, J., J M Burr, A Elders, J Earnshaw, Bachoo, Paul, C R Ramsay, Brittenden, Julie, Ramsay, Craig R., Gough, M., Chetter, I., Cotton, S. C., Lees, Tim, Tassie, E., T Lees, Campbell, Bruce, Wileman, Samantha, Campbell, M. K., Chetter, Ian, Campbell, B., Cotton, Seonaidh C, Cotton, Seonaidh C., Neil Stewart, Earnshaw, Jonothan, J Brittenden, Scotland, Graham, Norrie, J., P Bachoo, I Chetter   +64 more
core   +1 more source

Wireless, Adaptable and Fully Implantable Battery‐powered Devices for Optical Stimulation of the Spinal Cord in Small Rodents

Advanced Science, EarlyView.
Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh, Adan Moallemi, Elham Mohseni Vadeghani, Samuel Tretjakov, Brianna Tsuyuki, Alexander Golab, Benjamin Rever, Wolfram Tetzlaff, Dena Shahriari   +8 more
wiley   +1 more source