Results 181 to 190 of about 18,757 (301)

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin   +15 more
wiley   +1 more source

Per‐ and polyfluoroalkyl substances and hand osteoarthritis: data from the Osteoarthritis Initiative

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To explore whether biological levels of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS – reflecting the overall effect and accounting for correlations among each PFAS – relate to incident hand osteoarthritis (HOA) and progression.
Jeffrey B. Driban   +14 more
wiley   +1 more source

A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis   +9 more
wiley   +1 more source

Digital mammography, cancer screening: Factors important for image compression [PDF]

open access: yes
The use of digital mammography for breast cancer screening poses several novel problems such as development of digital sensors, computer assisted diagnosis (CAD) methods for image noise suppression, enhancement, and pattern recognition, compression ...
Blaine, G. James   +7 more
core   +1 more source

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova   +9 more
wiley   +1 more source

“We might be put into situations we are uncomfortable with, but not exactly told how to deal with them”: Health professional students' experiences questioning low‐value care practices during work‐integrated learning

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Health professions students often observe and practice alongside supervising health professionals during work‐integrated learning (WIL) to develop essential capabilities. While students may encounter practices they interpret as low‐value care during WIL, many hesitate to question or challenge these practices.
Melanie K. Farlie   +7 more
wiley   +1 more source

“Because everybody's different”: Co‐designing body donor program consent processes

open access: yesAnatomical Sciences Education, EarlyView.
Abstract While it is broadly accepted that body donation for anatomical education should rely on informed consent, consent processes vary substantially. Best practice guidelines for body donation are typically published by anatomical societies and may not reflect details valued by prospective donors or the educators and students who utilize donor ...
Georgina C. Stephens
wiley   +1 more source

Chest Radiograph Image Enhancement: A Total Variation Approach

open access: yesInternational Journal of Computer Applications, 2017
Peter A.   +3 more
openaire   +1 more source

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