Results 31 to 40 of about 164,141 (253)

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

Magnetic resonance imaging findings in Ghanaian patients presenting with low back pain: a single centre study

BMC Medical Imaging
Background Due to the high prevalence of low back pain which impacts the lives of those affected, several studies have explored findings associated with the lumbar spine (which is the affected anatomy) using magnetic resonance imaging (MRI).
Godwill Acquah, Derick Seyram Sule, Lawrence Fesi, Kofi Adesi Kyei, Jacob Leonard Ago, Dennison Agala, William K. Antwi   +6 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Comparison of Anatomical and Indication-Based Diagnostic Reference Levels (DRLs) in Head CT Imaging: Implications for Radiation Dose Management

International Journal of Biomedical Imaging
Conclusion:The study highlights that using anatomical DLP DRL values for specific indications in head CT scans can lead to underestimated or overestimated DLP values, making them less reliable for radiation management compared to indication-based DRLs ...
Benard Ohene-Botwe, Samuel Anim-Sampong, Robert Saizi   +2 more
doaj   +1 more source

The osteological use of diagnostic radiographs: Further material for osteoarchaeologists [PDF]

, 1996
This article discusses the use of radiography in ...
Lewis, Stephen J.
core  

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz, Carl D. Langefeld, Mary E. Comeau, Miranda C. Marion, Tyler P. Behymer, Lee A. Gilkerson, Padmini Sekar, Weihong Yuan, Vivek Khandwala, Brady J. Williamson, Thomas Maloney, Achala Vagal, Pierce Boyne, Kari Dunning, Matthew L. Flaherty, Steven J. Kittner, Prachi Mehndiratta, Gunjan Y. Parikh, Michael L. James, David Roh, Fernando D. Testai, Farhaan S. Vahidy, James Thornton, Ranjit Bagga, Daniel Woo, Stacie L. Demel   +25 more
wiley   +1 more source

Navigating challenges in radiography research: radiographers’ perspectives in Saudi Arabia [PDF]

PeerJ
Introduction Radiography is a crucial healthcare specialty that requires ongoing research to advance imaging technologies and techniques. Despite this, radiographers are faced with obstacles such as time constraints, lack of resources, and the need for ...
Faisal A. Alrehily, Walaa Alsharif, Yasser Aloufi, Ammar Alsaedi, Marwan Aljohani, Reem S. Alotaibi, Hamed Alshammari, Abdullah Fahad A. Alshamrani, Fahad H. Alhazmi, Abdulaziz Qurashi   +9 more
doaj   +2 more sources

The experiences of teleradiology end users regarding role extension in a rural district of the North West province: A qualitative analysis

African Journal of Primary Health Care & Family Medicine, 2020
Background: Teleradiology was implemented across South Africa, to provide reporting services to rural healthcare institutes without a radiologist. This is guided by standard operating procedure manuals (SOP) which standardise the quality of services ...
Hafsa Essop, Mable Kekana
doaj   +1 more source

THE INCIDENCE OF ULTRASOUND DIAGNOSED UTERINE ABNORMALITIES RELATED TO MISCARRIAGE RATES – A LOCAL AUDIT [PDF]

Romanian Journal of Medical Practice, 2019
Introduction. Uterine abnormalities are traditionally presented as the cause of pregnancy loss at specific time of pregnancy, mostly at the first or second trimester.
Alyaa M. Raheem, Hayder A. Al-shimmari, Shatha K. Abdul Kareem   +2 more
doaj   +1 more source

Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma, Rhonda Mittenzwei, Heather Maioli, Amanda Kirkland, C. Dirk Keene, Ramon Diaz‐Arrastia, Christine Mac Donald, Chiara Maffei, Brian L. Edlow, Amber L. Nolan   +9 more
wiley   +1 more source