Results 61 to 70 of about 94,191 (255)

Motor and Cognitive Outcome After Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease Harboring GBA1 Variant

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) is effective for Parkinson's disease (PD); however, its efficacy varies with genetic background, such as the GBA1 variant—the causative gene of Gaucher disease—associated with increased PD risk and cognitive decline after subthalamic nucleus (STN)‐DBS.
Hikaru Kamo, Genko Oyama, Mai Shimizu, Haruka Takeshige‐Amano, Takashi Ogawa, Wataru Sako, Noriko Nishikawa, Taku Hatano, Yuanzhe Li, Hiroyo Yoshino, Manabu Funayama, Masanobu Ito, Hirokazu Iwamuro, Atsushi Umemura, Nobutaka Hattori   +14 more
wiley   +1 more source

Apoptosis and genotoxicity effects of Zygophyllum album and Suaeda palaestina extracts on Ehrlich solid carcinoma in mice

Bulletin of the National Research Centre
Background Various medicinal plants and their bioactive compounds exhibited promising anticancer activities by inducing apoptosis, inhibiting angiogenesis, and modulating several signaling pathways in cancer cells.
Marwa M. El-Attar, Ekram S. Ahmad, Hedaya A. Kamel, Amal I. Hassan, Abdel-Fattah A. Awad, Fatthy M. Abdel-Tawab   +5 more
doaj   +1 more source

Special Issue ”Instruments and Methods for Cyclotron Produced Radioisotopes”

Instruments, 2019
The 17th Workshop on Targets and Target Chemistry (WTTC17) was held in Coimbra (Portugal) on 27−31 August 2018. A few months before, the 13th Workshop of the European Cyclotron Network (CYCLEUR) took place in Lisbon (Portugal) on 23−24 ...
Saverio Braccini, Francisco Alves
doaj   +1 more source

Early Diagnosis of Alzheimer's disease by NIRF Spectroscopy and Nuclear Medicine [PDF]

, 2011
There is an urgent need for the early detection of diseases such as Alzheimer’s (AD) and Cancers in order to enable their successful treatment. Cancer is the second major cause of death after Heart Disease, and AD is the third major cause of death
I. C. Baianu
core   +1 more source

Synthesis of Bioactive Glass Doped With Bismuth, Zinc, and Copper for Bone Regeneration: Structural and Hemodynamic Analysis Employing ANSYS Static Structural and Fluent Modeling

Nano Select, EarlyView.
Schematic representation of Bi–Zn–Cu doped bioactive glass synthesis, scaffold modelling, and computational analyses for bone tissue engineering and targeted radiotherapy applications in bone malignancies. ABSTRACT Bioactive glasses (BG) are heavily explored biomaterials especially for their bone and tissue regenerative property and biocompatibility ...
Anindita Adri, Nayeem Bin Zahid, Nazmul Hossain, Md Sahadath Hossain, Samina Ahmed, Abul Arafat, Sabrin A. Samad   +6 more
wiley   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Generation of radioisotopes for medical applications using high-repetition, high-intensity lasers

High Power Laser Science and Engineering
We used the PW high-repetition laser facility VEGA-3 at Centro de Láseres Pulsados in Salamanca, with the goal of studying the generation of radioisotopes using laser-driven proton beams.
Katarzyna Liliana Batani, Marcia R. D. Rodrigues, Aldo Bonasera, Mattia Cipriani, Fabrizio Consoli, Francesco Filippi, Massimiliano M. Scisciò, Lorenzo Giuffrida, Vasiliki Kantarelou, Stanislav Stancek, Roberto Lera, Jose Antonio Pérez-Hernández, Luca Volpe, I. C. Edmond Turcu, Matteo Passoni, Davide Vavassori, David Dellasega, Alessandro Maffini, Marine Huault, Howel Larreur, Louis Sayo, Thomas Carriere, Philippe Nicolai, Didier Raffestin, Diluka Singappuli, Dimitri Batani   +25 more
doaj   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

Small, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom, Jae Hun Ahn, Jung Yung Kim, Kyo Chul Lee, Yong Jin Lee, Sanoj Rejinold N, Jin‐Ho Choy   +6 more
wiley   +1 more source

Study of heat sensitive radioisotopes for temperature measurement application Final report [PDF]

Heat sensitive radioisotopes for temperature measurements in rocket nose ...
Hutchinson, H. D.
core   +1 more source

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

Small, EarlyView.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad, Shunping Han, Rifka Utami, Rafal Baker, Dina Helal, Zhuoni Li, Mark Tricklebank, Yannis Paloyelis, Julie Wang, Marija M. Petrinovic, Sukhi Bansal, Khuloud T. Al‐Jamal   +11 more
wiley   +1 more source