Results 151 to 160 of about 3,699,543 (339)

Sono‐Controllable Janus Hydrogel Platform for Sequential Tumor Eradication and Bone Regeneration in Metastatic Breast Cancer

open access: yesAdvanced Science, EarlyView.
Sequential tumor eradication and bone regeneration remain a significant challenge for patients with breast cancer bone metastases. This study develops a novel Janus hydrogel platform, which can achieve tumor elimination and bone repair under the action of different ultrasound frequencies.
Yitong Li   +12 more
wiley   +1 more source

CLINTERVENTIONAL protocol: a randomized controlled trial to evaluate clinical consultations and audiovisual tools for interventional radiology

open access: yesEuropean Radiology Experimental
Interventional radiology (IR) has evolved rapidly, but the clinical integration of interventional radiologists has not kept pace with technical advancements.
Pedro Blas García Jurado   +7 more
doaj   +1 more source

Focal Spot, Summer 1997 [PDF]

open access: yes, 1997
https://digitalcommons.wustl.edu/focal_spot_archives/1076/thumbnail ...

core   +1 more source

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

open access: yesAdvanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang   +14 more
wiley   +1 more source

Tumor‐Targeted FABP5/STING Cascade Promote Radiofrequency Ablation Induced Ferroptosis and Intratumoral Immune Rewiring in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Targeted FABP5 co‐delivery nanoparticles amplify RFA‐induced ferroptosis and intratumoral immune rewiring via STING/TBK1 pathway activation in HCC. The pH‐responsive lipid nanoshell was integrated with cyclic RGD peptide (cRGD) and red blood cell membrane (RBCM), and encapsulated with superparamagnetic iron oxide (SPIO) and sgFABP5 to construct FS@RBCM/
Bufu Tang   +16 more
wiley   +1 more source

A Novel Self‐Regulated, Non‐Directional Magnetic Thermos‐Brachytherapy 125I Seed Enhances Anticancer Efficacy by Rescuing Immune Escape

open access: yesAdvanced Science, EarlyView.
This work constructs magnetic nanoparticles (MNPs) and incorporates them with silver rods coated with 125I to form a novel composite seed, which exhibits direction‐independent and self‐regulated heating efficiency, as well as the capacity of preventing MNPs leakage and enabling repeated hyperthermia.
Bin Xu   +22 more
wiley   +1 more source

Interpretable Multimodal Fusion Model Enhances Postoperative Recurrence Prediction in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
An interpretable multimodal fusion model (RSA) integrating clinical, radiomic, and pathomic features is developed and validated to predict early postoperative recurrence in gastric cancer. The RSA model demonstrates superior predictive performance and holds potential for guiding adjuvant chemotherapy decisions and improving individualized patient ...
Ping'an Ding   +16 more
wiley   +1 more source

Simulator training for enhanced interventional radiology education

open access: yesScientific Reports
To address the challenges of staff shortages and the need to gain practical experience in interventional radiology by increasing attention in the medical curriculum, especially in combination with the opportunity to successfully gain hands-on experience,
Nina Kronner   +9 more
doaj   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

open access: yesAdvanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera   +12 more
wiley   +1 more source

EUS-guided portal pressure gradient measurement with a simple novel device: a human pilot study. [PDF]

open access: yes, 2018
Background and aimsPortal hypertension is a serious adverse event of liver cirrhosis. Recently, we developed a simple novel technique for EUS-guided portal pressure gradient (PPG) measurement (PPGM).
Chang, Kenneth J   +7 more
core  

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