Results 111 to 120 of about 173,192 (315)

Molecular theranostics: principles, challenges and controversies

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

Carbon, Nitrogen, and Corresponding Stable Isotope Signatures Reveal Channel Banks as Major Sediment Sources in a Tropical Agricultural Watershed

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Uncertainties about the applicability of δ13C and δ15N as tracers of sediment sources in tropical river basins highlight the need for more in‐depth investigations of these isotopes. This study therefore assessed the effectiveness of δ13C and δ15N signatures in discriminating sediment sources in an agricultural catchment in Northeast Brazil ...
Fábio Farias Amorim   +10 more
wiley   +1 more source

Assessment of Soil Erosion Over Six Decades in a Long‐Term Experiment Using Fallout 137Cs and RUSLE: A South American Case Study

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Soil erosion remains a major global concern affecting agricultural productivity and land sustainability. This study investigates the magnitude and variability of soil erosion in a long‐term experiment (LTE) established in 1963 in Colonia, Uruguay, aiming to compare the performance of the 137Cs tracer technique and the RUSLE model across ...
Marcos Tassano   +6 more
wiley   +1 more source

A Novel Method for Generating a Fused Ventilation–Perfusion Map Using CT‐Derived Ventilation and FDG‐PET for Lung Functional Avoidance in Radiotherapy: A Feasibility Study

open access: yesPrecision Radiation Oncology, EarlyView.
This study retrospectively analyzed two types of respiratory phase CT and PET/CT images of 20 lung cancer patients. After DIR and functional grading, three lung function images were developed, and their correlations and differences were evaluated. Abstract Background Pulmonary ventilation–perfusion function plays a crucial role in both radiotherapy ...
Suyan Bi   +4 more
wiley   +1 more source

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet   +8 more
wiley   +1 more source

Cutting‐edge advances in bicyclic peptide‐based radiotracers for cancer imaging and theranostics

open access: yesVIEW, EarlyView.
Abstract Along with successful clinical approval of radiopharmaceuticals targeting somatostatin receptor subtype 2 and prostate‐specific membrane antigen, peptide‐based radiotracers have garnered the increasing attention in cancer imaging and theranostics. As a newly emerging targeting ligand in recent years, bicyclic peptides have demonstrated immense
Hengyi Ou, Xiaobo Wang, Fei Kang
wiley   +1 more source

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