Results 131 to 140 of about 271,092 (363)

A Concept for Preoperative and Intraoperative Molecular Imaging and Detection for Assessing Extent of Disease of Solid Tumors

open access: yesOncology Reviews
The authors propose a concept of “systems engineering,” the approach to assessing the extent of diseased tissue (EODT) in solid tumors. We modeled the proof of this concept based on our clinical experience with colorectal carcinoma (CRC) and gastrinoma ...
Charles L. Hitchcock   +7 more
doaj   +1 more source

Real‐Time Monitoring of Carbon Steel Corrosion Under High‐Dose Gamma Irradiation Using Electrical Resistance Sensors Designed for Deep Geological Repository of Radioactive Waste

open access: yesMaterials and Corrosion, EarlyView.
Electrical (ER) corrosion sensors made of AISI 1010 carbon steel are tested under gamma irradiation (0.25–1.00 MGy) for deep geological radioactive waste disposal applications. Despite the high dose rates of this study, ER sensors remain reliable, showing no significant loss in measurement performances.
Johan Becker   +3 more
wiley   +1 more source

THE PROBLEMS OF USING EXEMPTION ACTIVITY VALUES FOR REGULATING THE MANAGEMENT OF SEALED RADIONUCLIDE SOURCES OF GAMMA-RADIATION

open access: yesРадиационная гигиена, 2018
The article focuses on the procedure for exemption of the sealed and unsealed radionuclide sources of gamma radiation from regulatory control. The contradictory nature of the existing set of exemption criteria has been noted, leading, in some cases, to ...
A. N. Barkovsky   +2 more
doaj   +1 more source

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller   +5 more
wiley   +1 more source

Current understanding of electroautotrophy and its relevance in astrobiology‐related research

open access: yesmLife, EarlyView.
Abstract Electroautotrophy—the use of extracellular electrons as the primary energy source for autotrophic metabolism—remains understudied compared to photoautotrophy and chemoautotrophy. Its occurrence in deep‐earth and deep‐sea environments suggests profound implications for astrobiology, yet electroautotrophic microorganisms remain poorly explored ...
Quansheng Wang, Maggie C. Y. Lau Vetter
wiley   +1 more source

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet   +8 more
wiley   +1 more source

Atypical presentation of pheochromocytoma as acute ischemic stroke and pulmonary embolism, a case report

open access: yesUroPrecision, EarlyView.
Abstract Background Pheochromocytoma is a rare catecholamine‐secreting tumor that often presents with symptoms such as hypertension, palpitations, and sweating due to excessive hormone production. In some cases, the catecholamine‐induced vasoconstriction and hypercoagulability associated with pheochromocytomas can lead to cerebrovascular accidents and ...
Mohannad N. AbuHaweeleh   +6 more
wiley   +1 more source

PET/NIR‐II fluorescence imaging and image‐guided surgery of breast cancer using a CD47‐specific nanobody

open access: yesVIEW, EarlyView.
A CD47‐targeted dual‐modal imaging probe combining positron emission tomography and second near‐infrared fluorescence enables precise preoperative tumor localization and intraoperative guidance for complete resection of breast cancer lesions, including metastases, offering a promising strategy to enhance surgical accuracy and improve clinical outcomes.
Jun Li   +9 more
wiley   +1 more source

Recent implications of FAPI PET in cardiac diseases

open access: yesVIEW, EarlyView.
Background: FAP, highly expressed in activated cardiac fibroblasts after injury, is the target for FAPI‐based PET imaging. What was done: This review examines the role of FAPI PET imaging across major cardiac conditions (myocardial infarction, hypertrophic cardiomyopathy, dilated cardiomyopathy, and cardiac amyloidosis) and critically evaluates its ...
Lan Wang   +4 more
wiley   +1 more source

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