Results 171 to 180 of about 209,267 (264)

Using Joint Models in Phase I Dose‐Finding Designs in Oncology: Considerations for Frequentist Approaches

Statistics in Medicine, Volume 45, Issue 23-24, October 2026.
ABSTRACT Dose‐finding trials for oncology studies are traditionally designed to assess safety in the early stages of drug development. With the rise of molecularly targeted therapies and immuno‐oncology compounds, biomarker‐driven approaches are increasingly importance.
Xijin Chen, Pavel Mozgunov, Richard D. Baird, Thomas Jaki   +3 more
wiley   +1 more source

Risk assessment of radionuclides in different environmental matrices in the State of Qatar, Arabian Gulf. [PDF]

Environ Geochem Health
Veerasingam S, Vinothini V, Ranjani M, Mohammad REA, Suresh G, Rajendran S, Sadasivuni KK, Ghani S, Al-Khayat F.   +8 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, Volume 7, Issue 5, October 2026.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Comparative Dosimetry of Single and Hybrid ¹⁷⁷Lu, ¹⁶¹Tb, and ⁹⁰Y in PSMA-Targeted Therapy. [PDF]

Diseases
Oni OM, Smith TAD.
europepmc   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, Volume 7, Issue 5, October 2026.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source

Linking In Vivo Imaging to Therapeutic Outcome with ¹³¹I, ¹⁷⁷Lu, ¹⁸⁸Re Nanoparticles. [PDF]

Int J Mol Sci
Finogenova Y, Lipengolts A, Klementyeva O, Shpakova K, Skribitsky V, Grigorieva E.   +5 more
europepmc   +1 more source

Seasonal Variations in Aerosol Trace Element Source Contributions and Deposition Fluxes to the North Pacific Subtropical Gyre

Global Biogeochemical Cycles, Volume 40, Issue 10, October 2026.
Abstract Trace elements deposited in the marine environment affect ocean biogeochemistry in numerous, complex ways. This study quantifies seasonal aerosol trace element (TE) fluxes and evaluates their variability and potential sources over a 2‐year period in the North Pacific subtropical gyre (NPSG). We established the Hawaii Aerosol Time Series (HATS),
C. Kollman, C. M. Marsay, D. C. Ohnemus, M. Stephens, E. S. Bates, M. J. Ricci, C. S. Buck   +6 more
wiley   +1 more source

Chemical Scaffolds Driving Modern Anticancer Drug Discovery and Radiotheranostics: Structural Determinants, Translational Opportunities and Future Perspectives. [PDF]

Pharmaceuticals (Basel)
Rusek M.
europepmc   +1 more source

Clinical History of the Theranostic Radionuclide Approach to Neuroendocrine Tumors and Other Types of Cancer: Historical Review Based on an Interview of Eric P. Krenning by Rachel Levine

Journal of Nuclear Medicine, 2017
Rachel Levine, E. Krenning
semanticscholar   +1 more source

Getting to the Core of the Matter—Assessing the Role of Replication in Metabarcoding‐Based sedaDNA

Molecular Ecology Resources, Volume 26, Issue 7, October 2026.
ABSTRACT Replication is central to most experimental and sampling designs, increasing inferential power and capturing fine‐scale data heterogeneity. However, its importance remains poorly evaluated in some ecological and evolutionary settings. This is the case of metabarcoding studies using DNA recovered from sedimentary archives, in which biological ...
Elena Baños, Clara Ras Segura, Erik J. De Boer, Andrew B. Cundy, Xavier Turon Barrera, Sandra Nogué, Luke E. Holman, Marc Rius   +7 more
wiley   +1 more source