Results 281 to 290 of about 179,601 (373)

Enhancing the Stability of ²¹¹At Radiopharmaceuticals: Insights from Ortho-Substituent Strategies. [PDF]

ACS Med Chem Lett
Zhao T, Liang SH.
europepmc   +1 more source

Site‐Specific Modification of Native IgGs with Flexible Drug‐Load

ChemBioChem, Volume 26, Issue 8, April 14, 2025.
ADC generation from native IgG: using short, positively charged peptides like RAK enables the direct modification of IgG at the glutamine Q295 without the need for engineering. Using azide‐ and thiol‐group containing RAK, the generation of ADCs with different drug‐to‐antibody ratios (DARs) is demonstrated and their properties analyzed in‐vitro and in ...
Jöri E. Wehrmüller, Julia C. Frei, Torsten Hechler, Michael Kulke, Andreas Pahl, Martin Béhé, Roger Schibli, Philipp R. Spycher   +7 more
wiley   +1 more source

Molecular theranostics: principles, challenges and controversies. [PDF]

J Med Radiat Sci
Currie G.
europepmc   +1 more source

A sampler for concentrating radionuclides from natural waters

, 1971
W.B. Silker, R.W. Perkins, H.G. Rieck
openalex   +1 more source

Expert panel on monitoring radiation doses from recurrent medical diagnostic procedures: Sixth Gilbert W. Beebe Webinar

Journal of Applied Clinical Medical Physics, Volume 26, Issue 4, April 2025.
Abstract Recurrent imaging is an essential tool for patient care but with an attendant dose from radiation exposure. Recurrent imaging has been the subject of increasing scrutiny and debate based largely on the risk from increasing cumulative doses. However, the accountability for and actions with recurrent imaging as a special component in the general
Donald P. Frush, Armin Ansari, James A. Brink, Ourania Kosti, David B. Larson, Martha S. Linet, Mahadevappa Mahesh, Ioannis Sechopoulos, Jenia Vassileva   +8 more
wiley   +1 more source

On the reduction of imaging time-points for dosimetry in radionuclide therapy. [PDF]

EJNMMI Phys
Gustafsson J, Taprogge J.
europepmc   +1 more source

Hydrology of the solid waste burial ground as related to potential migration of radionuclides, Idaho National Engineering Laboratory

, 1976
J.T. Barraclough, J.B. Robertson, V.J. Janzer, L.G. Saindon   +3 more
openalex   +2 more sources

Evaluating auto‐contouring accuracy in reduced CT dose images for radiopharmaceutical therapies: Denoising and evaluation of 177Lu DOTATATE therapy dataset

Journal of Applied Clinical Medical Physics, Volume 26, Issue 4, April 2025.
Abstract Purpose Reducing radiation dose attributed to computed tomography (CT) may compromise the accuracy of organ segmentation, an important step in 177Lu DOTATATE therapy that affects both activity and mass estimates. This study aimed to facilitate CT dose reduction using deep learning methods for patients undergoing serial single photon emission ...
Hung‐Te Yang, Kuan‐Yin Ko, Ching‐Ching Yang   +2 more
wiley   +1 more source

Efficient delivery of anlotinib and radioiodine by long circulating nano-capsules for active enhanced suppression of anaplastic thyroid carcinoma. [PDF]

J Nanobiotechnology
Zhang L, Zhu C, Huang S, Xu M, Li C, Fu H, Yin Y, Liang S, Wang H, Cui Z, Huang L.   +10 more
europepmc   +1 more source

An Anti‐CD147 Antibody−Drug Conjugate Mehozumab‐DM1 is Efficacious Against Hepatocellular Carcinoma in Cynomolgus Monkey

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Antibody‐drug conjugates are among the fastest‐growing drugs in oncology. It combines the potent killing activity of small molecular drugs and the high specific targeting of antibody drugs. Our in vitro and in vivo studies suggest that anti‐CD147 ADC Mehozumab‐DM1 potently inhibits hepatocellular carcinoma, and combining CD147‐ADCs and targeted therapy
Wan Huang, Liping Zhong, Ying Shi, Qingzhi Ma, Xiangmin Yang, Hongmei Zhang, Jing Zhang, Ling Wang, Kun Wang, Jingzhuo Li, Jie Zou, Xu Yang, Liu Yang, Qingmei Zeng, Lin Jing, Zhi‐Nan Chen, Yongxiang Zhao   +16 more
wiley   +1 more source