Results 51 to 60 of about 6,188,743 (292)

Biomarkers in Prostate-Specific Membrane Antigen Theranostics

open access: yesDiagnostics, 2021
Theranostics of prostate cancer (PC) represents a growing area of development of imaging agents and targeted radionuclide therapeutics against a major target, prostate specific membrane antigen (PSMA).
Panagiotis J. Vlachostergios   +2 more
doaj   +1 more source

Protocols for Dual Tracer PET/SPECT Preclinical Imaging

open access: yesFrontiers in Physics, 2020
Background: Multi-tracer PET/SPECT imaging enables different modality tracers to be present simultaneously, allowing multiple physiological processes to be imaged in the same subject, within a short time-frame.
Julia E. Blower   +11 more
doaj   +1 more source

Critical Appraisal of Radionuclide Calibrators and Gamma Cameras Prior to Lutetium-177 Internal Dosimetry at Two South African Hospitals

open access: yesWorld Journal of Nuclear Medicine, 2022
Introduction The functionality of radionuclide dose calibrator and nuclear medicine imaging systems hasa direct effect on the accuracy and preciseness of internal dosimetry evaluations.
Bronwin P. Van Wyk   +5 more
doaj   +1 more source

Efficient Synthesis of Macromolecular DO3A@Gn Derivatives for Potential Application in MRI Diagnostics: From Polymer Conjugates to Polymer Nanoparticles

open access: yesMacromolecular Chemistry and Physics, Volume 224, Issue 1, January 2023., 2023
Herein, poly(2‐oxazoline) homo‐ and copolymers are used for functionalization with the 1,4,7,10‐tetraazacyclododecane‐N,N,N,N‐tetraacetic acid chelator and subsequent complexation with Gn(III). The resulting conjugates are utilized for micelle and nanoparticle formation and are further analyzed and compared toward their relaxivity as a prerequisite for
Anne‐Larissa Kampmann   +2 more
wiley   +1 more source

Partial volume effect in SPECT & PET imaging and impact on radionuclide dosimetry estimates [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology, 2023
Objective(s): The spatial resolution of emission tomographic imaging systems can lead to a significant underestimation in the apparent radioactivity concentration in objects of size comparable to the resolution volume of the system. The aim of this study
Harry Marquis   +2 more
doaj   +1 more source

Fast full patient and radioisotope Monte Carlo simulations of targeted radionuclide therapy: introducing egs_mird [PDF]

open access: yesarXiv, 2022
BACKGROUND: Targeted Radionuclide Therapy (TRT) is a fast-growing field garnering much interest, however, dosimetry calculation techniques remain relatively simple. PURPOSE: To introduce egs_mird, a new Monte Carlo application built in EGSnrc which allows users to model full patient tissue and density (using clinical CT images) and radionuclide ...
arxiv  

Breast-Dedicated Radionuclide Imaging Systems

open access: yesJournal of Nuclear Medicine, 2016
Breast-dedicated radionuclide imaging systems show promise for increasing clinical sensitivity for breast cancer while minimizing patient dose and cost.
D. Hsu, D. Freese, C. Levin
semanticscholar   +1 more source

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Copper radionuclides for theranostic applications: towards standardisation of their nuclear data. A mini-review

open access: yesFrontiers in Chemistry, 2023
Copper has several clinically relevant radioisotopes and versatile coordination chemistry, allowing attachment of its radionuclides to biological molecules.
Mazhar Hussain   +5 more
doaj   +1 more source

Production of high purity $^{52g}$Mn from $^{nat}$V targets with $α$-beams at cyclotrons [PDF]

open access: yes, 2021
Radioisotope $^{52g}$Mn is of special interest for multimodal imaging. Using state-of-art nuclear reaction codes, we study the alternative nuclear reaction route $^{nat}$V($\alpha$,x)$^{52g}$Mn in comparison with the standard production routes based upon the use of chromium targets. The integral yields of $^{52g}$Mn and contaminants have been evaluated.
arxiv   +1 more source

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