Results 91 to 100 of about 30,778 (256)

Hypoxia-augmented chemotherapy potentiates imaging-guided combinatorial radionuclide-sonodynamic therapy for pancreatic cancer

Journal of Nanobiotechnology
Radionuclide therapy and chemotherapy are effective for pancreatic cancer, yet their efficacy is often limited by tumor hypoxia. In this study, manganese porphyrin (MnTTP) and tirapazamine (TPZ) were encapsulated in polylactic-co-glycolic acid (PLGA ...
Jie An, Kaile Chu, Xirong Li, Huizhu Ma, Qin Zhou, Chenliang Niu, Jie Gao, Junping Lv, Jianbo Cao, XinYu Zhang, Haitao Zhou, Hongliang Wang, Min Li, Zhifang Wu, Sijin Li   +14 more
doaj   +1 more source

From fixed activities to personalized treatments in radionuclide therapy: lost in translation? [PDF]

, 2017
Glenn Flux, Katarina Sjögreen Gleisner, Claudio Chiesa, Michael Laßmann, Nicolas Chouin, Jonathan Gear, Manuel Bardiès, Stéphane Walrand, Klaus Bacher, Uta Eberlein, Michael Ljungberg, Lidia Strigari, Eric P. Visser, Mark Konijnenberg   +13 more
openalex   +1 more source

Supplementary Figure from Targeted Radionuclide Therapy with Low and High-Dose Lutetium-177–Labeled Single Domain Antibodies Induces Distinct Immune Signatures in a Mouse Melanoma Model

, 2023
Thomas Ertveldt, Lien De Beck, Kirsten De Ridder, Hanne Locy, Wout de Mey, Cleo Goyvaerts, Quentin Lecocq, Hannelore Ceuppens, Yannick De Vlaeminck, Robin Maximilian Awad, Marleen Keyaerts, Nick Devoogdt, Matthias D’Huyvetter, Karine Breckpot, Ahmet Krasniqi   +14 more
openalex   +1 more source

Molecular Deconvolution of Circulating “Other Cells”: A Reliable Predictive Marker of Therapy Response and Survival in Neuroendocrine Tumor Patients Receiving 177Lu‐DOTATATE PRRT

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Purpose To assess the prognostic impact of pre‐treatment circulating other cells on treatment response and survival in neuroendocrine tumor (NET) patients receiving Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu‐DOTATATE. Methods Healthy donors (HDs, n = 81) and NET patients (n = 137) were analyzed.
Mahesh K. Padwal, Rahul V. Parghane, Sandip Basu, Bhakti Basu   +3 more
wiley   +1 more source

Targeted Radionuclide Therapy: Practical Applications and Future Prospects [PDF]

, 2016
Katherine Zukotynski, Hossein Jadvar, Jacek Capala, Frederic H. Fahey   +3 more
openalex   +1 more source

Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen‐Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Reactive oxygen species (ROS) can induce cancer cell apoptosis, which plays a crucial role in breast cancer therapy. Carnosic acid (CA) exerts an anti‐tumor effect via generating ROS or activating the mitochondria‐related apoptosis pathway in vitro and in vivo.
Xinyu Wang, Peng Xu, Sha Luan, Yuying Jiao, Yue Gao, Changjiu Zhao, Peng Fu   +6 more
wiley   +1 more source

Synthesis of Poly[APMA]-DOTA-Cu Conjugates for Interventional Radionuclide Therapy of Prostate Cancer: Assessment of Intratumoral Retention by Micro–Positron Emission Tomography

Molecular Imaging, 2007
To develop new radiopharmaceuticals for interventional radionuclide therapy of locally recurrent prostate cancer, poly[ N -(3-aminopropyl)methacrylamide] [poly(APMA)] polymers were synthesized by free radical precipitation polymerization in ...
Jianchao Yuan, Yezi You, Xin Lu, Otto Muzik, David Oupicky, Fangyu Peng   +5 more
doaj   +1 more source

Erratum to: The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours [PDF]

, 2013
Lisa Bodei, Jan Mueller‐Brand, Richard P. Baum, Marianne E. Pavel, Dieter Hörsch, M. Sue O’Dorisio, Thomas M. O’Dorisio, James R. Howe, Marta Cremonesi, D. J. Kwekkeboom, John J. Zaknun   +10 more
openalex   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

ChemBioChem, Volume 27, Issue 1, January 2026.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh, Rupesh R. Kurhade, Abrar A. M. Siddiqui, Shaikh Shahbaz A. Majeed, Thomas J. Webster, Mohammad Intakhab Alam, Abdul Wasy Zia, Md. Faiyazuddin   +7 more
wiley   +1 more source

Nanotechnology in Skin Cancer Therapy: Recent Progress in Targeted Delivery

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 1, January 2026.
ABSTRACT Skin cancer, encompassing melanoma and non‐melanoma types, remains a significant public health concern globally. Conventional therapies—such as surgery, radiotherapy, chemotherapy, and immunotherapy—are constrained by poor skin penetration, systemic toxicity, and high recurrence rates.
Huang‐Ping Yu, Ching‐Yun Hsu, Jia‐You Fang, Zih‐Chan Lin   +3 more
wiley   +1 more source