Results 131 to 140 of about 58,392 (301)

Hypoxia-augmented chemotherapy potentiates imaging-guided combinatorial radionuclide-sonodynamic therapy for pancreatic cancer

Journal of Nanobiotechnology
Radionuclide therapy and chemotherapy are effective for pancreatic cancer, yet their efficacy is often limited by tumor hypoxia. In this study, manganese porphyrin (MnTTP) and tirapazamine (TPZ) were encapsulated in polylactic-co-glycolic acid (PLGA ...
Jie An, Kaile Chu, Xirong Li, Huizhu Ma, Qin Zhou, Chenliang Niu, Jie Gao, Junping Lv, Jianbo Cao, XinYu Zhang, Haitao Zhou, Hongliang Wang, Min Li, Zhifang Wu, Sijin Li   +14 more
doaj   +1 more source

Synthesis of Poly[APMA]-DOTA-Cu Conjugates for Interventional Radionuclide Therapy of Prostate Cancer: Assessment of Intratumoral Retention by Micro–Positron Emission Tomography

Molecular Imaging, 2007
To develop new radiopharmaceuticals for interventional radionuclide therapy of locally recurrent prostate cancer, poly[ N -(3-aminopropyl)methacrylamide] [poly(APMA)] polymers were synthesized by free radical precipitation polymerization in ...
Jianchao Yuan, Yezi You, Xin Lu, Otto Muzik, David Oupicky, Fangyu Peng   +5 more
doaj   +1 more source

Systematic review and meta‐analysis of the efficacy and safety of [177Lu]Lu‐edotreotide ([177Lu]Lu‐DOTATOC) for the treatment of neuroendocrine tumors

Journal of Neuroendocrinology, EarlyView.
Abstract [177Lu]Lu‐edotreotide is a radiopharmaceutical therapy (RPT) targeting somatostatin receptors, which are commonly overexpressed on neuroendocrine tumors (NETs). This systematic literature review and meta‐analysis describes the efficacy and safety of [177Lu]Lu‐edotreotide in patients with NETs.
Richard P. Baum, Julia G. Fricke, Tristan Ruhwedel, Holger Amthauer, Erika Patricia Azorin‐Vega, Dieter Hörsch, Riccardo Laudicella, Vikalp Maheshwari, Martin A. Walter, Berna Degirmenci Polack, Simon F. Spiegl, Guillaume P. Nicolas   +11 more
wiley   +1 more source

Hair radioactivity as a measure of exposure to radioisotopes [PDF]

, 1972
Since many radioisotopes accumulate in hair, this tropism was investigated by comparing the radioactivity of shaved with plucked hair collected from rats at various time intervals up to 24 hrs after intravenous injection of the ecologically important ...
Flynn, A., Fratianne, R. B., Pories, W. J., Strain, W. H.   +3 more
core   +1 more source

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

Medicinal Research Reviews, Volume 46, Issue 1, Page 203-237, January 2026.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller, Nadia Bom Pedersen, Vladimir Shalgunov, Andreas Ingemann Jensen, Umberto Maria Battisti, Matthias Manfred Herth   +5 more
wiley   +1 more source

High‐Loaded Bismuth Oxide/Copper Silicone Rubber Composites and Their Application as Shielding Collar for I‐131 Treated Thyroid Cancer Patients

SPE Polymers, Volume 7, Issue 1, January 2026.
Development of high‐filler‐content silicone rubber composites containing up to 80 wt% bismuth oxide or copper, demonstrating significant I‐131 attenuation with retained flexibility and durability. ABSTRACT The development of flexible, non‐lead radiation‐shielding materials remains a critical challenge, particularly for I‐131 protection, where no ...
Kanaungnit Kingpetch, Supatporn Tepmongkol, Anchali Krisanachinda, Piyachai Khomein   +3 more
wiley   +1 more source

Treatment‐related changes in the prostate: past, present and future therapies

Histopathology, Volume 88, Issue 1, Page 40-52, January 2026.
Radiation therapy alters tumour morphology and immunoprofile in prostate cancer. Residual carcinoma shows distorted glandular architecture on H&E and loss of basal markers with preserved AMACR expression by immunohistochemistry, aiding in the recognition of treatment effect in prostate biopsies.
Katrina Collins, Liang Cheng
wiley   +1 more source

Image-Based Dosimetry of Radionuclide Therapy [PDF]

, 2013
Ilhan Lim
openalex   +1 more source

A Rapid and Safe Infusion Protocol for ¹⁷⁷Lu Peptide Receptor Radionuclide Therapy [PDF]

, 2020
Sander C. Ebbers, Maarten W. Barentsz, Bart de Keizer, Gerard C. Krijger, Marnix G. E. H. Lam, Arthur J. A. T. Braat   +5 more
openalex   +1 more source

A review on radiochromic film dosimetry in radiation therapy

Journal of Applied Clinical Medical Physics, Volume 26, Issue 12, December 2025.
Abstract Radiochromic films (RCFs) are ubiquitous in radiation oncology clinical and research settings to measure the radiation dose over a two‐dimensional (2D) area due to their high spatial resolution, water‐equivalency, and relative ease‐of‐use. Upon irradiation, the constituent monomers of the active layer of RCFs undergo polymerization, leading to
Arash Darafsheh, Hamid Ghaznavi
wiley   +1 more source