Results 141 to 150 of about 58,375 (292)

Production of Medical Radioisotopes with High Specific Activity in Photonuclear Reactions with $\gamma$ Beams of High Intensity and Large Brilliance

open access: yes, 2010
We study the production of radioisotopes for nuclear medicine in $(\gamma,x{\rm n}+y{\rm p})$ photonuclear reactions or ($\gamma,\gamma'$) photoexcitation reactions with high flux [($10^{13}-10^{15}$)$\gamma$/s], small diameter $\sim (100 \, \mu$m$)^2 ...
A. Bishayee   +53 more
core   +1 more source

Tumour‐targeted fluorescence‐guided surgery in gastrointestinal cancer: A systematic review of preclinical and clinical research

open access: yesClinical and Translational Medicine, Volume 16, Issue 3, March 2026.
Tumour‐targeted fluorescence‐guided surgery (Ttfgs) enhances intraoperative precision in gastrointestinal cancer treatment. Translation of (Ttfgs) into clinical practice is limited by heterogeneity, regulatory hurdles, biomarker variability and absence of phase III trials.
Aaya Darai   +7 more
wiley   +1 more source

Tocotrienols: A Review From Source to Therapeutic Applications

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño   +6 more
wiley   +1 more source

Artificial Intelligence and Prostate–Breast Cancer Biology: Recent Advances in Treatments and Perspectives — A Comprehensive Review

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims The therapeutic limitations of conventional cancer treatment currently deployed are driving the development and creation of new nano‐drugs. Prostate cancer (PCa) is a prevalent clinical problem in older men with a significant global incidence, with 1.5 million cases reported in 2022.
Russell B. O. Ouma   +2 more
wiley   +1 more source

Focal Spot, Spring/Summer 1980 [PDF]

open access: yes, 1980
https://digitalcommons.wustl.edu/focal_spot_archives/1026/thumbnail ...

core   +1 more source

Synthesis, Radiochemical Characterization, and Biodistribution of a 188Re Analogue of [131I]mIBG in a Neuroblastoma Xenograft Model

open access: yesJournal of Labelled Compounds and Radiopharmaceuticals, Volume 69, Issue 3, March 2026.
A 188Re analogue of [131I]mIBG was synthesized in moderate yields using 188Re‐4 + 1 chemistry. In vitro studies using SK‐N‐SH neuroblastoma cell lines demonstrated that the compound exhibited affinity for norepinephrine transporters expressed on these cancer cells.
Navin Sakhare   +11 more
wiley   +1 more source

Chromatin Accessibility in Cancer: Biological Functions, Mechanisms, Therapeutic Potential, and Future Directions

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia   +4 more
wiley   +1 more source

Combined VLA-4–Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma [PDF]

open access: bronze, 2018
Jae‐Yeon Choi   +7 more
openalex   +1 more source

Revisiting the segmentation threshold for Lu‐177 SPECT

open access: yesMedical Physics, Volume 53, Issue 3, March 2026.
Abstract Background The mostly used threshold‐based segmentation method for SPECT, i.e., 42% of the maximum intensity, was derived from 99mTc and may not be directly applicable to 177Lu. Purpose This study aims to revisit the optimal segmentation threshold for 177Lu SPECT.
Yibin Liu   +5 more
wiley   +1 more source

Bismuth Bicycles

open access: yesJournal of Peptide Science, Volume 32, Issue 3, March 2026.
Discovery, evolution and potential future applications of bismuth bicycle molecules—a novel class of therapeutics with unique properties. ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules.
Saan Voss   +8 more
wiley   +1 more source

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