Results 141 to 150 of about 58,087 (312)
Abstract Background Geant4, a Monte Carlo Simulation Toolkit extensively used in bio‐medical physics, is in continuous evolution to include newest research findings to improve its accuracy and to respond to the evolving needs of a very diverse user community.
Pedro Arce+57 more
wiley +1 more source
To develop new radiopharmaceuticals for interventional radionuclide therapy of locally recurrent prostate cancer, poly[ N -(3-aminopropyl)methacrylamide] [poly(APMA)] polymers were synthesized by free radical precipitation polymerization in ...
Jianchao Yuan+5 more
doaj +1 more source
Perspective for use of the radionuclide drugs in the treatment of malignant tumors in Russiaw
This article reviews perspective of the targeted radionuclide therapy (TRT) as one of the rapidly growing fields of nuclear medicine. The characteristics, features of action, advantages and disadvantages of the most used α- and β-emitters (223Ra, 213Bi ...
S. K. Zyryanov, K. E. Zatolochina
doaj +1 more source
Automatic bone marrow segmentation for precise [177Lu]Lu‐PSMA‐617 dosimetry
Abstract Background Bone marrow (BM) is the dominant dose‐limiting organ in [177Lu]Lu‐PSMA‐617 therapy for patients with metastasized castration resistant prostate cancer, where BM dosimetry is challenging due to segmentation. Purpose We aim to develop an automatic image‐based segmentation method on peri‐therapeutic sequential [177Lu]Lu‐PSMA‐617 images
Zhonglin Lu+8 more
wiley +1 more source
Inflammation is a phenomenon responsible for the perturbation of homeostasis in several levels, with many sources, such as infection, injury, and exposure to contaminants.
Bianca Costa+11 more
doaj
A novel fast strategy to calculate equieffective doses under different dose rate conditions
Abstract Background Radiopharmaceutical therapy (RPT) has gained notable attention for its potential in treating difficult cancers, with [177Lu]Lu‐DOTATATE being a notable example. However, the radiobiology of RPT is less understood compared to external beam radiotherapy (EBRT), and dosimetry protocols are not standardized.
Mark J. Macsuka+3 more
wiley +1 more source
Abstract Background Single‐photon emission computed tomography (SPECT) devices equipped with cadmium–zinc–telluride (CZT) detectors achieve high contrast resolution because of their enhanced energy resolution. Recently, thallium bromide (TlBr) has gained attention as a detector material because of its high atomic number and density.
Toshimune Ito+9 more
wiley +1 more source
Advancing Hyperspectral Targeted Alpha Therapy with Adversarial Machine Learning [PDF]
Targeted Alpha Therapy (TAT) has emerged as a promising modality for the treatment of various malignancies, leveraging the high linear energy transfer (LET) and short range of alpha particles to selectively irradiate cancer cells while sparing healthy tissue. Monitoring and optimizing TAT delivery is crucial for its clinical success.
arxiv
Decay data of radionuclides along the valley of nuclear stability for astrophysical applications [PDF]
Several directions of the demand of decay data in nuclear astrophysics are discussed for radionuclides near the valley of nuclear stability. The current decay data evaluation results have been presented for a number of radionuclides of astrophysical interest.
arxiv