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Comparative Evaluation of Release Profiles from Hydrogel, Oleogel, and Bigel Systems Containing Model Radiopharmaceuticals for Buccal Delivery. [PDF]
Güneş M +3 more
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Adverse reactions to radiopharmaceuticals: liver radiopharmaceuticals
Radiopharmaceuticals are radioactive compounds used in nuclear medicine, consisting of a radioactive moiety and a pharmaceutical part. Radiopharmaceuticals are used for diagnosis (predominantly) and therapy (to a lesser extent). Adverse drug reactions are undesirable, unexpected, often harmful drug responses that occur when the drug is administered in ...
Humeyra, Battal, Asuman Yekta, Ozer
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SPECT Radiopharmaceuticals for Dementia
Over the last decade the interest towards functional neuroimaging has gradually increased, especially in the field of neurodegenerative diseases. At present, diagnosis of dementia is mostly clinical. Numerous modalities of neuroimaging are today available, each of them allowing a different aspect of neurodegeneration to be investigated. Although during
Guidotti, Claudio +6 more
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Pitfalls With Radiopharmaceuticals
American Journal of the Medical Sciences, 2011There is a considerable body of evidence describing that the pharmacokinetics and pharmacodynamics of radiopharmaceuticals may be changed by a variety of drugs, disease states and in some cases, surgical procedures.: To systematically search the medical literature and review the published evidence on adverse reactions to radiopharmaceuticals.MEDLINE ...
Ralph Santos-Oliveira, Marcio Machado
exaly +3 more sources
2023
Radiopharmaceuticals (RPs) have revolutionized the fields of nuclear medicine, diagnostic imaging, and targeted therapy. The chapter begins by elucidating the brief explanation of production and design of RPs. This chapter focuses on newly produced diagnostic & therapeutic radiopharmaceuticals that are being employed in normal clinical settings as ...
Vipasha Sharma +4 more
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Radiopharmaceuticals (RPs) have revolutionized the fields of nuclear medicine, diagnostic imaging, and targeted therapy. The chapter begins by elucidating the brief explanation of production and design of RPs. This chapter focuses on newly produced diagnostic & therapeutic radiopharmaceuticals that are being employed in normal clinical settings as ...
Vipasha Sharma +4 more
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Bispidines for radiopharmaceuticals
Dalton Transactions, 2018Radiometal based radiopharmaceuticals for imaging and therapy require selective ligands (bifunctional chelators, BFCs) that form metal complexes, which are inert againsttrans-chelation under physiological conditions, linked to a biological vector, directing them to the targeted tissue.
Peter Comba +3 more
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Stability of 11C-labeled PET radiopharmaceuticals
The stability of widely used 11C-radiopharmaceuticals was investigated. The purity of many 11C-radiopharmaceuticals was found to be low even at the end of synthesis and to lower with time by radiolysis.
478497 +15 more
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International Journal of Radiation Oncology*Biology*Physics, 2006
The term "naked" radiopharmaceuticals, more appropriately, "unbound" radiopharmaceuticals, refers to any radioisotope used for clinical research or clinical purposes that is not attached to a chemical or biological carrier, and that localizes in various tissues because of a physiologic or chemical propensity/affinity, or secondary to focal anatomic ...
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The term "naked" radiopharmaceuticals, more appropriately, "unbound" radiopharmaceuticals, refers to any radioisotope used for clinical research or clinical purposes that is not attached to a chemical or biological carrier, and that localizes in various tissues because of a physiologic or chemical propensity/affinity, or secondary to focal anatomic ...
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