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Recent Breakthrough in 68Ga-Radiopharmaceuticals Cold Kits for Convenient PET Radiopharmacy.

Bioconjugate chemistry, 2021
68Ga-PET has emerged as an important diagnostic tool for precise detection and monitoring of oncological situations. Availability, cost, and radiosynthesis procedure are determining steps for success of a radioisotope/radiopharmaceutical in nuclear ...
Drishty Satpati
semanticscholar   +1 more source

Bispidines for radiopharmaceuticals

Dalton Transactions, 2018
Radiometal based radiopharmaceuticals for imaging and therapy require selective ligands (bifunctional chelators, BFCs) that form metal complexes, which are inert againsttrans-chelation under physiological conditions, linked to a biological vector, directing them to the targeted tissue.
Peter Comba   +3 more
openaire   +3 more sources

Pitfalls With Radiopharmaceuticals

The American Journal of the Medical Sciences, 2011
There is a considerable body of evidence describing that the pharmacokinetics and pharmacodynamics of radiopharmaceuticals may be changed by a variety of drugs, disease states and in some cases, surgical procedures.: To systematically search the medical literature and review the published evidence on adverse reactions to radiopharmaceuticals.MEDLINE ...
Márcio Machado, Ralph Santos-Oliveira
openaire   +3 more sources

Radiopharmaceuticals for Neuroendocrine Tumors

Seminars in Radiation Oncology, 2021
Neuroendocrine tumors (NETs) are a heterogeneous group of tumors that originate in endocrine tissues throughout the body. Peptide receptor radionuclide therapy (PRRT) has emerged as a promising therapeutic option for patients with locally advanced and/or metastatic disease refractory to standard of care treatment.
Hyun Jik Kim   +3 more
openaire   +3 more sources

The Regulation of Radiopharmaceuticals

JAMA: The Journal of the American Medical Association, 1985
To the Editor.— The recent editorial on the Food and Drug Administration's (FDA) role in the drug approval process is appropriate. 1 In our opinion, the FDA has shown concern about infringement upon the practice of medicine. 2 Such may not be said for the Nuclear Regulatory Commission (NRC), in its interpretation of its statutory authority to regulate
openaire   +3 more sources

Comparison of 5 Different PET Radiopharmaceuticals for the Detection of Recurrent Medullary Thyroid Carcinoma

Clinical Nuclear Medicine, 2020
Purpose The aim of this study is to investigate and compare the performance of different PET radiopharmaceuticals for the detection of recurrent medullary thyroid carcinoma (MTC) by performing a network meta-analysis (NMA) using direct comparison studies
Sang-Woo Lee   +3 more
semanticscholar   +1 more source

SPECT Radiopharmaceuticals for Dementia

Current Radiopharmaceuticals, 2014
Over the last decade the interest towards functional neuroimaging has gradually increased, especially in the field of neurodegenerative diseases. At present, diagnosis of dementia is mostly clinical. Numerous modalities of neuroimaging are today available, each of them allowing a different aspect of neurodegeneration to be investigated. Although during
Guidotti, Claudio   +6 more
openaire   +3 more sources

Nanoparticulate formulations of radiopharmaceuticals: Strategy to improve targeting and biodistribution properties.

Journal of labelled compounds & radiopharmaceuticals, 2020
Application of nanotechnology principles in drug delivery has created opportunities for treatment of several diseases. Nanotechnology offers the advantage of overcoming the adverse biopharmaceutics or pharmacokinetic properties of drug molecules, to be ...
P. Datta, Soumendranath Ray
semanticscholar   +1 more source

Radiopharmaceuticals labelled with Technetium

The International Journal of Applied Radiation and Isotopes, 1977
Abstract The ready availability and ideal nuclear properties of 99mTc has led to its widespread use for imaging purposes. In general the localization of the present radiopharmaceuticals is based on the ability of an organ to remove foreign substances from the blood. Further application of this ideal nuclide seems related to the development of methods
Stanley M. Levenson, W. C. Eckelman
openaire   +3 more sources

IAEA activities on 67Cu, 186Re, 47Sc Theranostic radionuclides and Radiopharmaceuticals.

Current Radiopharmaceuticals, 2020
Despite interesting properties, the use of 67Cu, 186Re and 47Sc theranostic radionuclides in preclinical studies and clinical trials is curtailed by their limited availability due to a lack of widely established production methods.
A. Jalilian   +18 more
semanticscholar   +1 more source

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