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Radiopharmaceutical Dosimetry in Pediatrics

Radiology, 1968
The increasing use of radionuclides in medical diagnosis and research requires that we investigate further the radiation exposure from these procedures. Although information is frequently available for adults (1–3), only occasional reference is found to radiation doses received by children (4), a group in which there should be much concern about ...
James G. Kereiakes   +3 more
openaire   +5 more sources

PSMA-Targeted Radiopharmaceuticals for Imaging and Therapy.

Seminars in nuclear medicine, 2019
As described in more detail in other contributions in this issue of Seminars in Nuclear Medicine, prostate-specific membrane antigen (PSMA) has become one of the most promising molecular targets in nuclear medicine.
H. Wester, M. Schottelius
semanticscholar   +1 more source

Design and Challenges of Radiopharmaceuticals.

Seminars in nuclear medicine, 2019
This review describes general concepts with regard to radiopharmaceuticals for diagnostic or therapeutic applications that help to understand the specific challenges encountered during the design, (radio)synthesis, in vitro and in vivo evaluation and ...
K. Vermeulen   +3 more
semanticscholar   +1 more source

Renal radiopharmaceuticals—An update

Seminars in Nuclear Medicine, 1982
Noninvasive radionuclide procedures in the evaluation of renal disease have been accepted increasingly as effective and valuable alternatives to older clinical methods. The development of suitable radiopharmaceuticals labeled with high photon intensity radionuclides and with 99mTc in particular has stimulated this modality during the last few years ...
L. Rao Chervu, M. Donald Blaufox
openaire   +4 more sources

MEDICINAL RADIOPHARMACEUTICAL CHEMISTRY OF METAL RADIOPHARMACEUTICALS

COSMOS, 2012
Metal complexes have been used as medicinal compounds. Metals have advantageous features over organic compounds. Significant applications of metal complexes are in the field of nuclear medicine. Radiopharmaceuticals are drugs containing radioisotopes used for diagnostic and therapeutic purposes.The generalized targeting strategy for molecular imaging ...
openaire   +2 more sources

“Naked” radiopharmaceuticals

International Journal of Radiation Oncology*Biology*Physics, 2006
The term "naked" radiopharmaceuticals, more appropriately, "unbound" radiopharmaceuticals, refers to any radioisotope used for clinical research or clinical purposes that is not attached to a chemical or biological carrier, and that localizes in various tissues because of a physiologic or chemical propensity/affinity, or secondary to focal anatomic ...
openaire   +2 more sources

Quality Control of Radiopharmaceuticals [PDF]

open access: possible, 1979
Since radiopharmaceuticals are intended for human administration, it is imperative that they undergo strict quality control measures. Basically, quality control involves several specific tests and measurements that ensure the purity, potency, product identity, biologic safety, and efficacy of radiopharmaceuticals.
openaire   +1 more source

A New Radiopharmaceutical for Placentography

Radiology, 1964
Radioisotopic placentography requires accurate localization of the maternal component of placental circulation by detection of a circulating radionuclide confined to the maternal intravascular space. Sodium-24 chloride was the tracer first employed in placentography (2) but its rapid extravascular diffusion was disadvantageous.
Elmer E. Stickley   +2 more
openaire   +3 more sources

Drug interactions with radiopharmaceuticals

European Journal of Nuclear Medicine, 1994
Considerable information on documented drug and radiopharmaceutical interactions has been assembled in a tabular form, classified by the type of nuclear medicine study. The aim is to provide a rapid reference for nuclear medicine staff to look for such interactions.
Stuart Hesslewood, Emmeline Leung
openaire   +3 more sources

Radiochemistry and radiopharmaceuticals

Annual Reports Section "A" (Inorganic Chemistry), 2006
Following last year’s precedent this section of Annual Reports will review not only recent progress in radiochemistry, including isotope production and environmental aspects, but also in the production of radiopharmaceuticals and their use in nuclear medicine for imaging.
David S. Urch, Michael J. Welch
openaire   +2 more sources

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