Results 61 to 70 of about 46,065 (228)

Early Levodopa Therapy in Tyrosine Hydroxylase Deficiency

Movement Disorders Clinical Practice, EarlyView.
Claudio M. de Gusmao, Roser Pons, Ganeshwaran H. Mochida, Laura Silveira‐Moriyama, Fernando Kok   +4 more
wiley   +1 more source

Probabilistic Mapping of Magnetic Resonance‐Guided Focused Ultrasound (MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor‐Dominant Parkinson's Disease: Insights from a German Cohort

Movement Disorders, EarlyView.
Precise targeting in magnetic resonance‐guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor‐dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = −12.4, y = −17 ...
Jonas Krauss, Neeraj Upadhyay, Veronika Purrer, Valeri Borger, Marcel Daamen, Hannah Weiland, Angelika Maurer, Carsten Schmeel, Alexander Radbruch, Markus Essler, Ullrich Wüllner, Henning Boecker   +11 more
wiley   +1 more source

The efficacy of Stereotactic body radiation therapy and the impact of systemic treatments in oligometastatic patients from prostate cancer

Cancer Medicine, 2018
Background Diagnoses of oligometastatic prostate cancer (PC) increased in the recent years thanks to the advancement in imaging and more effective systemic therapies.
Ciro Franzese, Paolo Andrea Zucali, Lucia Di Brina, Giuseppe D'Agostino, Pierina Navarria, Davide Franceschini, Armando Santoro, Marta Scorsetti   +7 more
doaj   +1 more source

Radiosurgery for Vestibular Schwannomas

Journal of the Chinese Medical Association, 2005
Radiosurgery has been established as an important alternative to microsurgery. We report our experience with radiosurgery for tumor control and the complications of unilateral vestibular schwannomas.We reviewed our early experience regarding clinical presentation, management and outcomes in 45 patients with acoustic schwannomas who underwent gamma ...
Chuan-Fu Huang, Wen-Shan Liu, Kao-Lun Wang, Hsiu-Kuan Lo, Hsien-Tang Tu   +4 more
openaire   +3 more sources

A Novel α‐Synuclein K58N Missense Variant in a Patient with Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a complex multifactorial disorder with a genetic component in about 15% of cases. Multiplications and point mutations in SNCA gene, encoding α‐synuclein (aSyn), are linked to rare familial forms of PD. Objective Our goal was to assess the clinical presentation and the biological effects of a novel K58N ...
Mohammed Al‐Azzani, Sandrina Weber, Nagendran Ramalingam, Maria Ramón, Liana Shvachiy, Gonçalo Mestre, Michael Zech, Kevin Sicking, Alain Ibáñez de Opakua, Vidyashree Jayanthi, Leslie Amaral, Aishwarya Agarwal, Aswathy Chandran, Susana R. Chaves, Juliane Winkelmann, Claudia Trenkwalder, Maike Schwager, Silke Pauli, Ulf Dettmer, Claudio O. Fernández, Janin Lautenschläger, Markus Zweckstetter, Ruben Fernandez‐Busnadiego, Brit Mollenhauer, Tiago Fleming Outeiro   +24 more
wiley   +1 more source

A Time-Series Approach for Machine Learning-Based Patient-Specific Quality Assurance of Radiosurgery Plans

Bioengineering
Stereotactic radiosurgery (SRS) for multiple brain metastases can be delivered with a single isocenter and non-coplanar arcs, achieving highly conformal dose distributions at the cost of extreme modulation of treatment machine parameters.
Simone Buzzi, Pietro Mancosu, Andrea Bresolin, Pasqualina Gallo, Francesco La Fauci, Francesca Lobefalo, Lucia Paganini, Marco Pelizzoli, Giacomo Reggiori, Ciro Franzese, Stefano Tomatis, Marta Scorsetti, Cristina Lenardi, Nicola Lambri   +13 more
doaj   +1 more source

Use of hypofractionated radiotherapy regimens after organ-sparing surgery for Stages I–IIA breast cancers

Опухоли женской репродуктивной системы, 2014
There have been recent reports on the expediency of applying postoperative hypofractionated accelerated radiotherapy (RT) regimens in patients who have undergone breast-sparing surgery.
Yu. V. Efimkina, I. A. Gladilina, M. I. Nechushkin   +2 more
doaj   +1 more source

Radiosurgery for Gliomas

US Neurology, 2009
Stereotactic radiosurgery is a neurosurgical modality that involves delivering a large dose of focused radiation to a lesion while sparing the surrounding normal brain tissue. The biological properties of some gliomas, specifically relating to their oxygenation and invasiveness, can make them good targets for stereotactic radiosurgery.
Jay Jagannathan, Jason P. Sheehan, Nader Pouratian   +2 more
openaire   +2 more sources

Advances and Future Perspectives for the Management of Non‐Small Cell Lung Cancer in Australia: A Narrative Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Lung cancer remains Australia's leading cause of cancer death. With new screening and evolving therapies, equitable access and workforce readiness are essential. This review discusses current and emerging treatments for NSCLC in Australia, clinical trials underway, and future directions in delivering optimal, accessible care nationwide.
Lauren Julia Brown, Graham Meredith, Bo Gao, Pei Ding, Harriet Gee, Inês Pires da Silva, Adnan Nagrial, Eric Hau   +7 more
wiley   +1 more source

Comparison of the Efficacy of Different First‐Line Therapies for EGFR L858R‐Mutated NSCLC Patients With Brain Metastases

Cancer Science, EarlyView.
The combination of third‐generation EGFR‐TKIs with chemotherapy shows enhanced efficacy in patients with EGFR 21L858R mutation and BMs compared to other treatments. Future prospective clinical trials are warranted to assess this combination in this population.
Jing Chen, Yin Pan, Baishen Zhang, Meichen Li, Hui Yu, Mingjie Yu, Likun Chen   +6 more
wiley   +1 more source