Results 81 to 90 of about 98,702 (366)

Current trends in glioblastoma multiforme treatment: radiation therapy and immune checkpoint inhibitors. [PDF]

open access: yes, 2013
Glioblastoma multiforme (GBM) is the most common primary brain cancer. Even with aggressive combination therapy, the median life expectancy for patients with GBM remains approximately 14 months.
Jackson, Christopher   +5 more
core   +1 more source

Utility of Magnetic Resonance Imaging (Imaging) in Target Volume Definition for Radiosurgery of Acoustic Neuromas

open access: yesInternational Journal of Cancer and Clinical Research, 2019
Aim: Acoustic neuromas, also known as vestibular schwannomas are benign and slow-growing tumors arising from neural crest-derived Schwann cells. Treatment of acoustic neuromas targets to achieve local control while preserving hearing without comprimising
O. Sager   +7 more
semanticscholar   +1 more source

Impact of enhanced leaf model on dose calculation accuracy in single‐isocenter multitarget stereotactic radiosurgery treatments

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Single‐isocenter multitarget (SIMT) radiosurgery has become increasingly popular as advancement in planning and delivery systems have made this approach clinically viable. With targets varying in size and distance from isocenter, SIMT plans are highly complex with dynamic multileaf collimator (MLC) motion.
Hem Moktan   +3 more
wiley   +1 more source

Systemic therapy‐based split‐course stereotactic body radiation therapy

open access: yesPrecision Radiation Oncology, Volume 6, Issue 4, Page 306-320, December 2022., 2022
Abstract Purpose Given the therapeutic toxicity of concurrent chemoradiotherapy, the dose of chemotherapy is always limited. Hence, the question of how to administer adequate chemotherapy to synchronize stereotactic body radiation therapy (SBRT) treatment strategy for maximizing the benefits of neoadjuvant therapy to improve prognosis is a challenging ...
Rong Zheng   +3 more
wiley   +1 more source

Results of Gamma Knife Radiosurgery in Acromegaly

open access: yesInternational Journal of Endocrinology, 2012
Objective. Single-session radiosurgery with Gamma Knife (GK) may be a potential adjuvant treatment in acromegaly. We analyzed the safety and efficacy of GK in patients who had previously received maximal surgical debulking at our hospital. Methods.
Alberto Franzin   +4 more
doaj   +1 more source

Substantially elevated serum glutamate and CSF GOT-1 levels associated with cerebral ischemia and poor neurological outcomes in subarachnoid hemorrhage patients

open access: yesScientific Reports, 2023
Brain injury and cerebral vasospasm during the 14 days after the subarachnoid hemorrhage (SAH) are considered the leading causes of poor outcomes.
Silvia Snider   +11 more
doaj   +1 more source

A Multiobjective Approach for Sector Duration Optimization in Stereotactic Radiosurgery Treatment Planning [PDF]

open access: yesarXiv, 2021
Sector duration optimization (SDO) is a problem arising in treatment planning for stereotactic radiosurgery on Gamma Knife. Given a set of isocenter locations, SDO aims to select collimator size configurations and irradiation times thereof such that target tissues receive prescribed doses in a reasonable amount of treatment time, while healthy tissues ...
arxiv  

The radiosurgery fractionation quandary: single fraction or hypofractionation?

open access: yesNeuro-Oncology, 2017
Stereotactic radiosurgery (SRS), typically administered in a single session, is widely employed to safely, efficiently, and effectively treat small intracranial lesions.
J. Kirkpatrick   +5 more
semanticscholar   +1 more source

Stereotactic radiotherapy for metastatic brain tumors: A comparative analysis of dose distributions among VMAT, Helical TomoTherapy, CyberKnife, Gamma Knife, and ZAP‐X

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract This study evaluates various radiotherapy techniques for treating metastatic brain tumor (BT), focusing on non‐coplanar volumetric modulated arc radiotherapy (NC‐VMAT), coplanar VMAT (C‐VMAT), Helical TomoTherapy (HT), CyberKnife (CK), Gamma Knife (GK), and ZAP‐X.
Toshihiro Suzuki   +9 more
wiley   +1 more source

Deep Learning Based Segmentation of Various Brain Lesions for Radiosurgery [PDF]

open access: yesarXiv, 2020
Semantic segmentation of medical images with deep learning models is rapidly developed. In this study, we benchmarked state-of-the-art deep learning segmentation algorithms on our clinical stereotactic radiosurgery dataset, demonstrating the strengths and weaknesses of these algorithms in a fairly practical scenario.
arxiv  

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