Results 81 to 90 of about 73,957 (300)

Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson's disease (PD). A better understanding of the neurobiological sources of such interindividual differences is necessary to personalize DRT prescribing, inform future clinical ...
Alex I. Wiesman   +5 more
wiley   +1 more source

The efficacy of Stereotactic body radiation therapy and the impact of systemic treatments in oligometastatic patients from prostate cancer

open access: yesCancer Medicine, 2018
Background Diagnoses of oligometastatic prostate cancer (PC) increased in the recent years thanks to the advancement in imaging and more effective systemic therapies.
Ciro Franzese   +7 more
doaj   +1 more source

Stereotactic radiosurgery for vestibular schwannomas. [PDF]

open access: yes, 2018
Stereotactic radiosurgery (SRS) maintains an important role in managing vestibular schwannoma (VS). Long-term clinical data have clearly established the safety and efficacy of the procedure for managing Koos low grade to intermediate grade VS ...
Braunstein, Steve, Ma, Lijun
core  

Cerebral arteriovenous malformations : usability of Spetzler-Martin and Spetzler-Ponce scales in qualification to endovascular embolisation and neurosurgical procedure [PDF]

open access: yes, 2018
Purpose: Arteriovenous malformations (AVMs) are connected with cerebral haemorrhage, seizures, increased intracranial pressure, headaches, mass effect, and ischaemia symptoms.
Baron, Jan   +8 more
core   +1 more source

Radiosurgery for hypothalamic hamartomas

open access: yesNeurosurgical Focus, 2008
✓ Radiosurgery plays an important role in the treatment of refractory seizures induced by hypothalamic hamartomas (HHs). These lesions, deeply located and surrounded by a delicate vascular and neuronal network, are often associated with catastrophic epilepsy leading to progressive cognitive and behavioral deterioration.
Romanelli, Pantaleo   +2 more
openaire   +4 more sources

Positron Emission Tomography Imaging in Clinical Trials for Parkinson's Disease: Applications of Metabolic Brain Network Approach

open access: yesMovement Disorders, EarlyView.
ABSTRACT Neuroimaging with positron emission tomography (PET) has been instrumental in elucidating neurobiological mechanisms behind therapeutical trials in Parkinson's disease (PD). A variety of medical and neurosurgical interventions have been evaluated using many radioligands that reveal molecular basis for target engagement and brain responses in ...
Vijay Dhawan   +4 more
wiley   +1 more source

EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement Disorder

open access: yesMovement Disorders, EarlyView.
ABSTRACT Background Congenital mirror movement disorders (CMMs) are clinically and genetically heterogeneous in human patients. CMMs have not been documented to occur spontaneously in animals. Objective The objective of this work was to document the first case of CMMs spontaneously occurring in Weimaraner dogs and to identify the underlying genetic ...
Cleo Schwarz   +11 more
wiley   +1 more source

Impact of use of optical surface imaging on initial patient setup for stereotactic body radiotherapy treatments [PDF]

open access: yes, 2019
Purpose To evaluate the effectiveness of surface image guidance (SG) for pre‐imaging setup of stereotactic body radiotherapy (SBRT) patients, and to investigate the impact of SG reference surface selection on this process.
Al‐Hallaq HA   +3 more
core   +2 more sources

Use of hypofractionated radiotherapy regimens after organ-sparing surgery for Stages I–IIA breast cancers

open access: yesОпухоли женской репродуктивной системы, 2014
There have been recent reports on the expediency of applying postoperative hypofractionated accelerated radiotherapy (RT) regimens in patients who have undergone breast-sparing surgery.
Yu. V. Efimkina   +2 more
doaj   +1 more source

Central Neurocytoma: A Review of Clinical Management and Histopathologic Features. [PDF]

open access: yes, 2016
Central neurocytoma (CN) is a rare, benign brain tumor often located in the lateral ventricles. CN may cause obstructive hydrocephalus and manifest as signs of increased intracranial pressure. The goal of treatment for CN is a gross total resection (GTR),
Bui, Timothy T   +10 more
core   +2 more sources

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