Results 1 to 10 of about 2,768 (130)

C-methionine-PET-guided Gamma Knife radiosurgery boost as adjuvant treatment for newly diagnosed glioblastomas. [PDF]

Surg Neurol Int, 2021
Background: The most common glial tumor is the glioblastoma, and the prognosis remains dismal despite a multimodal therapeutic approach. The role of radiosurgery for the treatment of glioblastomas has been evaluated in several studies with some benefit at the recurrent stage.
Jacobo JA, Buentello M, Del Valle R.
europepmc   +4 more sources

Phase I trial of dose-escalated stereotactic radiosurgery (SRS) boost for unfavorable locally advanced oropharyngeal cancer [PDF]

Radiation Oncology, 2020
Background and purpose Patients with locally advanced oropharynx squamous cell carcinoma have suboptimal outcomes with standard chemoradiation. Here, we evaluated toxicity and oncologic outcomes of dose escalation using radiosurgical boost for patients ...
Prashant Vempati, Aditya N. Halthore, Sewit Teckie, Zaker Rana, Emile Gogineni, Jeffrey Antone, Honglai Zhang, Mihaela Marrero, Kristin Beadle, Douglas K. Frank, Mohamed Aziz, Doru Paul, Maged Ghaly   +12 more
doaj   +3 more sources

Dosimetric Comparison of Upfront Boosting With Stereotactic Radiosurgery Versus Intraoperative Radiotherapy for Glioblastoma [PDF]

Frontiers in Oncology, 2021
PurposeTo simulate and analyze the dosimetric differences of intraoperative radiotherapy (IORT) or pre-operative single-fraction stereotactic radiosurgery (SRS) in addition to post-operative external beam radiotherapy (EBRT) in Glioblastoma (GB ...
Gustavo R. Sarria, Zuzanna Smalec, Thomas Muedder, Jasmin A. Holz, Davide Scafa, David Koch, Stephan Garbe, Matthias Schneider, Motaz Hamed, Hartmut Vatter, Ulrich Herrlinger, Frank A. Giordano, Leonard Christopher Schmeel   +12 more
doaj   +3 more sources

A phase 2 trial of stereotactic radiosurgery boost after surgical resection for brain metastases. [PDF]

Int J Radiat Oncol Biol Phys, 2014
To evaluate local control after surgical resection and postoperative stereotactic radiosurgery (SRS) for brain metastases.A total of 49 patients (50 lesions) were enrolled and available for analysis. Eligibility criteria included histologically confirmed malignancy with 1 or 2 intraparenchymal brain metastases, age≥18 years, and Karnofsky performance ...
Brennan C, Yang TJ, Hilden P, Zhang Z, Chan K, Yamada Y, Chan TA, Lymberis SC, Narayana A, Tabar V, Gutin PH, Ballangrud Å, Lis E, Beal K.   +13 more
europepmc   +4 more sources

Case Report: Multimodal management of a rare pediatric astroblastoma using proton beam therapy and Gamma Knife radiosurgery—a case report and literature review [PDF]

Frontiers in Oncology
IntroductionAstroblastoma is an infrequent glial tumor, with the MN1-altered subtype recognized in the 2021 WHO classification. This report details the management of a 4-year-old girl diagnosed with CNS WHO Grade 3 MN1-altered astroblastoma, also found ...
Xijia Zhang, Xinfa Wang, Weihai Ning, Jianfeng Liang, Yonglong Jin, Yuqian Nie, Jie Wang, Zishen Wang, Wei Wang, Jun Zhao, Jingjing Kong, Lu Yang, Dongxue Zhou, Yue Zou, Masashi Mizumoto, Shosei Shimizu, Shosei Shimizu   +16 more
doaj   +2 more sources

Stereotactic radiosurgery boost to the resection cavity for cerebral metastases: Report of overall survival, complications, and corticosteroid protocol.

Surg Neurol Int, 2013
This report focuses on the overall survival and complications associated with treatment of cerebral metastases with surgical resection followed by stereotactic radiosurgery (SRS). Management and complications of corticosteroid therapy are underreported in the literature but represent an important source of morbidity for patients.Fifty-nine consecutive ...
Kellogg RG, Straus DC, Choi M, Chaudhry TA, Diaz AZ, Muñoz LF.   +5 more
europepmc   +3 more sources

Treatment Planning Methods for Dose Painting by Numbers Treatment in Gamma Knife Radiosurgery [PDF]

Advances in Radiation Oncology
Purpose: Dose painting radiation therapy delivers a nonuniform dose to tumors to account for heterogeneous radiosensitivity. With recent and ongoing development of Gamma Knife machines making large-volume brain tumor treatments more practical, it is ...
Benjamin Z. Tham, PhD, Dionne M. Aleman, PhD, Håkan Nordström, PhD, Nelly Nygren, MSc, Catherine Coolens, PhD   +4 more
doaj   +2 more sources

OS05.5.A DOSE ESCALATED SPINE RADIOSURGERY FOR RADIORESISTANT SPINAL METASTASES UTILIZING SIMULTANEOUS INTEGRATED BOOST [PDF]

Neuro Oncol
Abstract BACKGROUND Spine stereotactic body radiosurgery (SSRS) delivers ablative doses of radiation with sub-millimeter precision leading to high rates of local control with minimal toxicity. Treatment dose, fractionation and technique vary from institution to institution.
Ghia, A J, Bernard, V, Iskander, G, Rooney, M, De, B, Briere, T M, Tatsui, C E, Bishop, A, Perni, S, Tom, M, Wang, C, Beckham, T, Yeboa, D N, McAleer, M, Li, J, Amini, B, Rhines, L D   +16 more
europepmc   +2 more sources

Escalating a Biological Dose of Radiation in the Target Volume Applying Stereotactic Radiosurgery in Patients with Head and Neck Region Tumours

Biomedicines, 2022
Background: The treatment of head and neck tumours is a complicated process usually involving surgery, radiation therapy, and systemic treatment. Despite the multidisciplinary approach, treatment outcomes are still unsatisfactory, especially considering ...
Paweł Polanowski, Krzysztof Składowski, Dorota Księżniak-Baran, Aleksandra Grządziel, Natalia Amrogowicz, Jolanta Mrochem-Kwarciak, Agnieszka Pietruszka, Marek Kentnowski, Katarzyna Polanowska   +8 more
doaj   +1 more source

Stereotactic Radiotherapy Boost in Treatment of Persistent Periocular Sebaceous Carcinoma after Surgery

Biomedicines, 2023
Sebaceous carcinoma is a rare malignancy that should be treated with surgical resection. Nonetheless, a dynamic and aggressive course of the disease may disqualify a patient from this treatment.
Paweł Polanowski, Aleksandra Nasiek, Aleksandra Grządziel, Ewa Chmielik, Agnieszka Pietruszka, Krzysztof Składowski, Katarzyna Polanowska   +6 more
doaj   +1 more source