Results 171 to 180 of about 829,320 (360)

Neo-adjuvant radiotherapy in rectal cancer

World Journal of Gastroenterology, 2013
In rectal cancer treatment, attention has focused on the local primary tumour and the regional tumour cell deposits to diminish the risk of a loco-regional recurrence. Several large randomized trials have also shown that combinations of surgery, radiotherapy and chemotherapy have markedly reduced the risk of a loco-regional recurrence, but this has not
openaire   +2 more sources

Survival benefit of adjuvant therapy completion with early initiation for patients with pancreatic ductal adenocarcinoma

Annals of Gastroenterological Surgery, EarlyView.
Adjuvant completion with early initiation may contribute to the improved survival of patients with pancreatic ductal adenocarcinoma. Abstract Aim To evaluate the prognostic effect of initiation timing and completion of adjuvant therapy in patients with pancreatic ductal adenocarcinoma.
Kenjiro Okada, Kenichiro Uemura, Tatsuaki Sumiyoshi, Ryuta Shintakuya, Kenta Baba, Takumi Harada, Yasutaka Ishii, Shiro Oka, Yoshiaki Murakami, Shinya Takahashi   +9 more
wiley   +1 more source

Cost‐effectiveness analysis of postoperative surveillance for stage IV colorectal cancer in Japan: An economic modeling study

Annals of Gastroenterological Surgery, EarlyView.
This economic evaluation used a Markov state‐transition model to analyze the cost‐effectiveness of surveillance strategies recommended by various academic societies. This study found that the surveillance program proposed by the Japanese Society for Cancer of the Colon and Rectum (JSCCR) was the most cost‐effective, with an incremental cost ...
Fumio Tsukamoto, Shunsuke Tsukamoto, Takeharu Kato, Hiroshi Nagata, Yasuyuki Takamizawa, Konosuke Moritani, Yusuke Kinugasa, Minoru Esaki, Yukihide Kanemitsu, Ataru Igarashi   +9 more
wiley   +1 more source

JulianA.jl -- A Julia package for radiotherapy [PDF]

arXiv
The importance of computers is continually increasing in radiotherapy. Efficient algorithms, implementations and the ability to leverage advancements in computer science are crucial to improve cancer care even further and deliver the best treatment to each patient. Yet, the software landscape for radiotherapy is fragmented into proprietary systems that
arxiv  

Procarbazine, CCNU and vincristine (PCV) versus temozolomide chemotherapy for patients with low-grade glioma: a systematic review. [PDF]

, 2018
Low-grade gliomas (LGG) encompass a heterogeneous group of tumors that are clinically, histologically and molecularly diverse. Treatment decisions for patients with LGG are directed toward improving upon the natural history while limiting treatment ...
Das, Sunit, Hafazalla, Karim, Jaja, Blessing, Perry, James R, Sahgal, Arjun   +4 more
core   +1 more source

The impact of delayed adjuvant chemotherapy on survival in gastric cancer patients with and without preoperative chemotherapy

Annals of Gastroenterological Surgery, EarlyView.
Delayed initiation of adjuvant chemotherapy (AC) is associated with significantly poorer postoperative survival in patients with gastric cancer, irrespective of whether preoperative chemotherapy was administered. These findings emphasize the importance of timely AC initiation to improve long‐term outcomes in this patient population.
Masataka Shimonosono, Takaaki Arigami, Daisuke Matsushita, Yusuke Tsuruda, Ken Sasaki, Kenji Baba, Takao Ohtsuka   +6 more
wiley   +1 more source

Promoter Methylation of DNA Repair Genes Predicts Disease-free Survival of Gastric Adenocarcinoma after Adjuvant Radiotherapy

Molecular Therapy: Oncolytics, 2020
The relentless debate on postoperative adjuvant radiotherapy in gastric adenocarcinoma (GA) has been lasting for decades. In this study, a new biomarker, named promoter methylation burden of DNA repair genes (RPMB), was established to identify the ...
Ning An, Zhuang Yu, Xin-Jia He, Yuan-Yuan Zhao, Li Yu, Yong-Chun Zhang, Hai-Jun Lu, Xue Yang   +7 more
doaj  

Prognostic factors for patients with esophageal cancer who achieve pathological complete response in the primary tumor after upfront chemotherapy or chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
Male gender and pathological lymph node metastasis are independent poor prognostic factors in patients with esophageal cancer who receive upfront treatment followed by surgery and achieved pathological complete response of the primary tumor. Among patients without pathological lymph node metastasis, the upfront chemotherapy group showed significantly ...
Masaaki Motoori, Koji Tanaka, Hiroshi Miyata, Makoto Yamasaki, Osamu Shiraishi, Atsushi Takeno, Tomoki Makino, Keijiro Sugimura, Takushi Yasuda, Yuichiro Doki   +9 more
wiley   +1 more source

Impact of primary tumor clinicopathological factors on prognosis after hepatic resection for rectal liver metastases

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study evaluates the prognostic factors in patients undergoing curative hepatic resection for rectal cancer liver metastases. It identifies lateral lymph node metastasis and perineural invasion as significant prognostic factors. Moreover, patients with these factors required nonsurgical treatment in the early postoperative period ...
Tomofumi Uotani, Takeshi Takamoto, Satoshi Nara, Daisuke Ban, Takahiro Mizui, Konosuke Moritani, Shunsuke Tsukamoto, Yukihide Kanemitsu, Tsutomu Fujii, Minoru Esaki   +9 more
wiley   +1 more source

A Large Language Model Pipeline for Breast Cancer Oncology [PDF]

arXiv
Large language models (LLMs) have demonstrated potential in the innovation of many disciplines. However, how they can best be developed for oncology remains underdeveloped. State-of-the-art OpenAI models were fine-tuned on a clinical dataset and clinical guidelines text corpus for two important cancer treatment factors, adjuvant radiation therapy and ...
arxiv