Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang+18 more
wiley +1 more source
Neoadjuvant treatment and premastectomy radiotherapy: oncological and surgical outcomes. [PDF]
Bannier M+4 more
europepmc +1 more source
The potential radiosensitization target PFKFB3 is related to response to radiotherapy in SweBCG91RT: a randomized clinical trial with long-term follow-up. [PDF]
Egelberg M+8 more
europepmc +1 more source
Adjuvant chemotherapy plus radiation for locally advanced endometrial cancer [PDF]
al, et, Mutch, David, Powell, Matthew A.
core +1 more source
Abstract Background Radiotherapy (RT) is a key treatment modality in cancer therapy, utilizing high‐energy radiation to directly kill tumor cells. Recent research has increasingly highlighted RT's potential to indirectly enhance antitumor immunity. However, this immune activation alone often fails to generate sustained systemic antitumor responses.
Xuejiao Han+11 more
wiley +1 more source
Oncologic outcomes following neoadjuvant immunochemotherapy in locally advanced oral squamous cell carcinoma. [PDF]
Li G, Wang J, Fang Q, Dai L, Du W.
europepmc +1 more source
Combating cancer immunotherapy resistance: a nano‐medicine perspective
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong+10 more
wiley +1 more source
Contemporary Patterns of Care for Low-Grade Glioma in Australia and New Zealand. [PDF]
Maddula M+6 more
europepmc +1 more source
Clinicopathological features and patterns of treatment of patients with endometrial cancer in Brazil. [PDF]
Arenhardt MP+3 more
europepmc +1 more source
Leveraging real-world data for continuous evaluation of computational clinical practice guidelines. [PDF]
Ebben KCWJ+7 more
europepmc +1 more source