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Chemotherapy as an Adjuvant to Radiotherapy
1967The rationale of combining a chemotherapeutic agent with radiation therapy can be on one of two hypotheses: 1. Agents like 5-fluorouracil (5-FU) or 5-bromodeoxyuridine (5-BUdR) have been shown to be radiation sensitizers (Bagshaw, 1961; Berry and Andrews, 1962; Bosch et al., 1958; Djordjevic and Szybalski, 1960, Kaplan et al., 1961, 1962 ...
Robert D. Lindberg +6 more
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The role of adjuvant chemotherapy and radiotherapy for cholangiocarcinoma
Best Practice & Research Clinical Gastroenterology, 2015Cholangiocarcinomas are rare cancers arising from the epithelia of the biliary tract. The only prospect of curative therapy is with surgery. However, relapse rates are high with five-year survival rates typically around 20-30%. Involved resection margins and spread to local lymph nodes are associated with a higher risk of relapse.
Juan W. Valle +2 more
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Adjuvant Radiotherapy for Melanoma
Archives of Otolaryngology - Head and Neck Surgery, 1989At the 31st annual meeting of the American Society for Head and Neck Surgery, held in San Francisco, Calif, April 5 and 6, 1989, Drs Scott Stern and James Suen, Little Rock, Ark, reported a retrospective study of the use of adjuvant radiotherapy in 30 patients with mucosal and advanced or recurrent cutaneous head and neck melanoma.
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Adjuvant radiotherapy in resectable pancreatic carcinoma
European Journal of Surgical Oncology (EJSO), 2002Pancreatic cancer is a near fatal disease. External beam radiotherapy and intraoperative radiation therapy (IORT) has been proposed with the aim to improve clinical outcome in resectable tumors. The aim of this study is to assess the feasibility and outcome in patients with cT1-3 pancreatic cancer, treated with surgery, external beam radiotherapy and ...
Morganti, A G +9 more
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INDICATIONS FOR ADJUVANT RADIOTHERAPY IN ENDOMETRIAL CARCINOMA
Hematology/Oncology Clinics of North America, 1999This article examines the impact of prognostic factors, adjuvant therapy, and randomized trials on the overall survival of patients with endometrial cancer. The potential role of radiation therapy as an adjuvant therapy, as well as the role of lymph node dissection, in the treatment of endometrial carcinomas is reviewed.
Margareta Fredstorp +2 more
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Adjuvant chemo-radiotherapy in ampullary cancers
European Journal of Surgical Oncology (EJSO), 2005Patterns of failure following surgical treatment of ampullary cancers indicate that up to 45% of patients develop loco-regional recurrence. The effect of adjuvant chemo-radiotherapy on survival and loco-regional control is not yet established in this malignancy.From January 1989 to December 2000, 113 patients underwent pancreatico-duodenectomy for ...
Palat Balachandran +6 more
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Adjuvant Radiotherapy for Breast Cancer
JAMA: The Journal of the American Medical Association, 1976DESPITE the diverse modifications of the classical Halsted mastectomy, which have been popularized in the past several decades, the adherents to the use of postoperative irradiation, particularly in patients found to have had cancerous axillary nodes at surgery, have remained steadfast.
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Adjuvant radiotherapy for phyllodes tumor of breast
Radiation Oncology Investigations, 1998Our purpose was to examine the role of radiotherapy in the management of phyllodes tumor of the breast. Eight patients were treated with adjuvant radiotherapy for nonmetastatic phyllodes tumor of the breast at the M.D. Anderson Cancer Center between December 1988-August 1993.
Gunar K. Zagars +3 more
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Overview of Adjuvant Radiotherapy for Breast Cancer
1988Two papers by Cuzick et al. (1987 a, b) have recently been published in which mortality results from all available mature randomized trials of adjuvant radiotherapy are updated and analyzed collectively. Briefly, these overviews, which were based on individual patient data for over 10000 patients with more than 6000 deaths, showed conclusively that ...
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