Results 191 to 200 of about 35,736 (252)

Conversion Therapy for cT4b and M1 Esophageal Squamous Cell Carcinoma: A Comprehensive Systematic Review

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We systematically reviewed conversion therapy for esophageal squamous cell carcinoma and propose a response‐based treatment strategy for cT4b and M1 disease. For cT4b, we emphasize definitive chemoradiotherapy with timed re‐evaluation and selective salvage or chemoselection to surgery; for M1, conversion is reserved for limited‐burden responders with ...
Eisuke Booka, Hiroya Takeuchi
wiley   +1 more source

Clinical Significance of Copper Chaperone for Superoxide Dismutase in Colorectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Targeting Cu transport proteins is an innovative therapeutic approach for combating cancer. However, the mechanisms underlying the malignant potential of Cu transport proteins remain largely unknown. To address this issue, we focused on the oncogenic potential of copper chaperones for superoxide dismutase (CCS) in colorectal cancer (
Nobuo Takiguchi   +15 more
wiley   +1 more source

Postoperative Impact of Anti‐Inflammatory Drug on Cancer Recurrence in Patients With Locally Advanced Gastric Cancer After Curative Gastrectomy: A Pilot Retrospective Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Anti‐inflammatory drugs may be effective in improving recurrence‐free survival after radical gastrectomy in patients with pStage II or III gastric cancer. ABSTRACT Background Elevated postoperative inflammation is associated with reduced recurrence‐free survival (RFS) after gastrectomy in patients with gastric cancer, independent of postoperative ...
Ryota Matsui   +7 more
wiley   +1 more source

The Influence of Surgeons' Gender on Surgical Outcomes in Laparoscopic Right Hemicolectomy: A Japanese Nationwide Retrospective Cohort Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study analyzed 58 503 laparoscopic right hemicolectomies for colon cancer in Japan between 2018 and 2022, comparing outcomes between male and female surgeons. No significant differences were found in surgical mortality or severe complications. Tailored surgical training programs for female surgeons may further enhance surgical outcomes.
Akihisa Matsuda   +10 more
wiley   +1 more source

Intratumoral Fusobacterium nucleatum Drives Cancer‐Associated Fibroblasts Enrichment and Immune Exclusion in Esophageal Squamous Cell Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Fusobacterium nucleatum contributes to the progression of ESCC by inducing NF‐κB–mediated inflammatory signaling in tumor cells and promoting CAFs activation. Its presence may facilitate immune exclusion and tumor invasion through stromal remodeling. Furthermore, F.
Takashi Ofuchi   +9 more
wiley   +1 more source

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