Results 181 to 190 of about 300,304 (238)
Smart Molecules, EarlyView.The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou +4 more
wiley +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Head and neck cancer (HNC) patients are advised to undergo dental extraction of teeth with poor prognosis prior to radiotherapy (RT) initiation to prevent osteoradionecrosis (ORN). However, insufficient healing time may result in persistent extraction wounds during RT, which constitute a potential risk factor for ORN, whereas ...
Nuo‐Zhou Liu +4 more
wiley +1 more source
Outcomes and Trends of Anal Squamous Cell Carcinoma in Queensland: A 26‐Year Review
ANZ Journal of Surgery, EarlyView.Anal squamous cell carcinoma incidence and mortality increased substantially in Queensland over 26 years, while survival outcomes remained unchanged. Evolving HPV prevention and screening strategies offer opportunities to reduce future disease burden, but substantial implementation barriers exist.
Amanda G. Liesegang +3 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Perineal vulvar squamous cell carcinoma was identified in 147 of 571 cases. Owing to the anatomical proximity of these tumors to the anus, treatment selection may present considerable clinical challenges. The majority of patients (53%) underwent surgical treatment alone, whereas 23% received surgery combined with adjuvant radiotherapy and 24% were ...
Karin Kjölhede +4 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo +3 more
wiley +1 more source
British Journal of Haematology, EarlyView.A comparison between bead‐based and cell‐based assays for autoantibody detection in childhood neutropenia revealed substantial discordance between platforms. Bead‐based methods should be complemented with cell‐based methods for optimal diagnostic sensitivity. Incorporating pro‐LL‐37 and ANC measurements into the clinical workup of childhood neutropenia
Paul Ratcliffe +3 more
wiley +1 more source
Long‐term oncological outcomes from a prospective cohort of patients with localised prostate cancer
BJU International, EarlyView.Objectives To report long‐term oncological outcomes for men with clinically localised prostate cancer (PCa) treated with contemporary modalities in a population‐based United States cohort. Patients and Methods The Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study prospectively enrolled men with clinically localised PCa from ...
Avi S. Baskin +17 more
wiley +1 more source
Outcomes of Radiotherapy for WHO Grade 2 Meningioma: Survival, Local Control, and Prognostic Factors. [PDF]
Medicina (Kaunas)Habiboğlu R +8 more
europepmc +1 more source
Brain Pathology, EarlyView.Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar +12 more
wiley +1 more source
Editorial: Optimizing radiotherapy for cervical cancer efficacy toxicity and brachytherapy integration. [PDF]
Front OncolVergalasova I, Jiang C, Song T, Lombe D.
europepmc +1 more source