ABSTRACT Glioblastoma (GBM) is the most aggressive type of primary brain tumor, and its invasive properties contribute significantly to incomplete surgical resection and tumor recurrence. Despite extensive clinical efforts to mitigate GBM invasion, targeted therapies against GBM stem cells (GSCs), which drive invasion, remain incompletely understood ...
Rui Niu +3 more
wiley +1 more source
The LBX2-AS1-miR-491-5p-PKM2 Positive Feedback Loop Promotes Radiation Resistance of Esophageal Cancer by Enhancing Glycolysis. [PDF]
Zhang F, Wang Z, Yao X, Zhang Q.
europepmc +1 more source
Tocotrienols: A Review From Source to Therapeutic Applications
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño +6 more
wiley +1 more source
Losartan Protects Against Radiation-Induced Testicular Damage by Modulating Oxidative Stress, Testosterone Levels, and Metabolic Profile. [PDF]
Spadella MA +5 more
europepmc +1 more source
Advanced extracellular vesicle immunotherapy
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang +6 more
wiley +1 more source
Exploring the role of intestinal microbiota in mitigating acute radiation-induced intestinal injury through high-energy X-ray FLASH radiotherapy via metagenomic analysis. [PDF]
Du H +14 more
europepmc +1 more source
ABSTRACT Background Patients with head and neck cancer (HNC) often experience deteriorated health‐related quality of life (HRQoL) and loss of body weight and muscle mass. The primary aim was to determine if a home‐based exercise program, aiming to increase physical activity (PA), could reduce muscle mass loss and fatigue.
Camilla Wallmander +8 more
wiley +1 more source
Dosimetric characterization of a Varex VF-80/μXHP x-ray unit using open-ended applicators for superficial radiotherapy. [PDF]
Zeeshan M +5 more
europepmc +1 more source
From Semantic Modeling to Precision Radiotherapy: An AI Framework Linking Radiobiology, Oncology, and Public Health Integration. [PDF]
de Souza FG +6 more
europepmc +1 more source
New modalities for ultra-high dose rate irradiation and FLASH experiments. [PDF]
Adrian G +4 more
europepmc +1 more source

