Results 161 to 170 of about 36,702 (248)

RUNX1/SLAMF3 Axis Drives Immunosuppression to Contribute to Colorectal Cancer Liver Metastasis by Blocking Phagocytosis and Depleting C1QC+ Tumor‐Associated Macrophages

Advanced Science, EarlyView.
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo, Xiaoli Jin, Lan Huang, Dejia Zeng, Nan Zhang, Shiyu Tang, Shu Luo, Samina Ejaz Syed, Ruiwu Dai, Qiu Li, Shufang Liang   +10 more
wiley   +1 more source

A comparative study of different parameter estimation methods for predictive models of Normal Tissue Complication Probability (NTCP) of radiation-induced temporal lobe injury following intensity-modulated radiotherapy in nasopharyngeal carcinoma. [PDF]

BMC Cancer
OuYang H, Liu Y, He X, Zhang J, Tao L, Liu M, Ding J, Hu R, Hu J, Huang Z, Deng S, Wu J, Xu Z, Luo Q, Zeng L.   +14 more
europepmc   +1 more source

Salvage esophagectomy for unresectable locally advanced esophageal squamous cell carcinoma: Significant or not?

Annals of Gastroenterological Surgery, EarlyView.
Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki, Makoto Sakai, Takayoshi Watanabe, Makoto Sohda, Ken Shirabe   +4 more
wiley   +1 more source

Application and effect evaluation of microsurgical resection combined with intensity-modulated radiation therapy in the treatment of intracranial solitary fibrous tumor/hemangiopericytoma. [PDF]

Medicine (Baltimore)
Jiang J, Qu X, Wang H, Zhang C, Deng Q, Xu X, Qiu J, Qu L, Yi Y.   +8 more
europepmc   +1 more source

Prognostic Value of Serum Insulin‐Like Growth Factor‐1 in Patients With Anal Fistula Treated by Incision‐Thread‐Drawing Surgery

Annals of Gastroenterological Surgery, EarlyView.
IGF‐1 levels above 174.9 ng/mL were associated with better wound healing and lower postoperative inflammation. Higher IGF‐1 levels correlated with improved anal function at 7 and 14 days post‐surgery. ABSTRACT Background Anal fistula is a chronic condition characterized by an abnormal tract between the anal canal and perianal skin, often leading to ...
Zhijun Wu, Xuexue Yin, Jing Li
wiley   +1 more source

Clinical Impact of Radiotherapy in Steroid-Refractory Graves' Orbitopathy. [PDF]

Cureus
Escobar Peralta E, García Ramírez JM, Ordoñez CHH, Bautista Hernández MY.   +3 more
europepmc   +1 more source

Development and Application of Organic Sonosensitizers in Cancer Therapy

Aggregate, EarlyView.
This review provides a comprehensive overview of organic sonosensitizers employed in cancer treatment, describing their underlying mechanisms and structure‐activity relationship in terms of sonodynamic therapy. The significance of nanotechnology and combination therapy with other oncological modalities (photothermal therapy, photodynamic therapy, etc.)
Yuhan Ding, Yuchen Yang, Omer Aras, Feifei An, Mengjiao Zhou, Yichao Chai   +5 more
wiley   +1 more source

Neurocognitive impact of different irradiation modalities for patients with grade I-II skull base meningioma: a prospective multi-arm cohort study (CANCER COG). [PDF]

Radiat Oncol
Lesueur P, Joly F, Clarisse B, Lequesne J, Stefan D, Balosso J, Lange M, Thureau S, Capel A, Castera M, Legrand B, Goliot N, Grellard JM, Tessonnier T, Castel H, Valable S.   +15 more
europepmc   +1 more source

Construction of Active Sites‐Accessible Au8 Clusters for Intensive Tumor Pyroptosis

Aggregate, EarlyView.
Ethynylferrocene (EFc) was utilized to engineer molecular‐like gold nanoclusters (NCs) with accessibly catalytic centers, resulting in NCs exhibiting excellent peroxidase‐like activity and the ability to radiosensitize, leading to the production of intracellular oxidative stress and activation of pyroptosis.
Qiu‐Xu Zang, Wei‐Tong Chen, Wenjing Zhang, Zhao‐Yang Wang, Xi‐Yan Dong, Runping Han, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Etiological Factors and Development of a Predictive Model for Urinary Tract Infections in Cervical Cancer Patients Undergoing Intensity-Modulated Radiotherapy. [PDF]

Infect Drug Resist
Yao Y, Tao L, Ma L, Fan Y, Zheng D, Wang J, Chen W.   +6 more
europepmc   +1 more source