Results 241 to 250 of about 962,920 (362)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Impact of radiotherapy on survival outcomes in metastatic neuroblastoma a propensity score matched SEER database analysis. [PDF]

Sci Rep
Aierken A, Atabieke F, Li SX, Li K.
europepmc   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Novel marker genes and small molecule drugs for radiotherapy resistance in cervical cancer identified based on single-cell multi-omics analysis. [PDF]

Discov Oncol
Liu Y, Pan X, Zhang X, Tan B, Ran R, Liu L, Yang L, Wang Z.   +7 more
europepmc   +1 more source

Radiotherapy in locally advanced cancer of the breast. Adjunct to standard therapy [PDF]

, 1967
Ruth Guttmann
openalex   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

125I inhibits the progression of cervical cancer by upregulating the HSF1/PU.1/SYK signaling pathway and consequently enhancing the apoptotic response mediated by ROS/USP7/P53. [PDF]

Sci Rep
Fan X, Liang X, Guo Y, Jin G, Ming D, An X.   +5 more
europepmc   +1 more source

Measurements of Biological Effects and Physical Parameters of Neutrons from the9Be(3He, n)11C Reaction; Possibilities for Fast Neutron Radiotherapy [PDF]

, 1968
J.J. Broerse, G.W. Barendsen
openalex   +1 more source

Comparative efficacy of surgery and radiotherapy in achieving local control in Kimura disease: a retrospective analysis of treatment outcomes. [PDF]

Front Oncol
Lv W, Chen Y, Wang X, Li S, Liu F, Hong J.   +5 more
europepmc   +1 more source

Oxygenation in Radiotherapy of Malignant Disease of the Upper Air Passages [Abridged] [PDF]

, 1964
I. Churchill‐Davidson
openalex   +1 more source