Results 231 to 240 of about 531,735 (303)

Precision Oncology via Radiotherapy-Triggered Drug Delivery: Mechanisms, Molecular Engineering, and Clinical Translation. [PDF]

Adv Sci (Weinh)
Jiang J, Zhang T, Dong J, Sun W.
europepmc   +1 more source

ALDH2 Suppresses Ferroptosis and Promotes Bortezomib Resistance in Multiple Myeloma Through the KEAP1‐NRF2 Feedback Loop

Advanced Science, EarlyView.
ALDH2, which is overexpressed in multiple myeloma, competitively binds KEAP1 to stabilize NRF2 by blocking its ubiquitin‐proteasomal degradation. Stabilized NRF2 translocates into the nucleus to upregulate the expression of GPX4. In parallel, NRF2 binds to the ALDH2 promoter to regulate its transcription, forming a positive feedback loop that represses
Ruonan Shao, Chengcheng Liu, Xinpei Deng, Jindong Xie, Wenjian Liu, Bin Yang, Lingrui Liu, Cailu Song, Lei Li, Hua Wang, Hailin Tang   +10 more
wiley   +1 more source

Expert Consensus on the Standardized Diagnosis, Treatment, and Management of Cancer in High-Altitude Regions of China. [PDF]

Cancer Innov
Li Y, Li F, Bai X, Li Y, Bai C, Chang Q, Guo C, Di J, Dong Q, Da M, Li Z, Liu Z, Liang H, Luo Y, Ren D, Yu P, Ma R, Wang M, Zhao X, Zhao F, Shen G, Feng Z, Wang H, Zhou S, Wei W, Chen S, Wang L, Du F, Tseyang, Xu H, Ling X, Xu G, Guo W, Zhao Y, Sang D, Feng H, Deqingwangmu, Gesangdeji, Basangdunzhu, Bianbazhaxi, Guo Y, Tao X, Bai G, Yang W, Luo H, Lei Y, Cidanwangjiu, Ma F, Wu D, Zhao J.   +49 more
europepmc   +1 more source

Updated dosimetric comparison of HDR interventional radiotherapy including ⁶⁰Co sources versus VMAT and electron beam therapy for NMSC. [PDF]

Radiat Environ Biophys
Sajjad S, Shahban M, Rosa E, Fionda B, Mehmood H, Kakakhel MB, Tagliaferri L, De Spirito M, Placidi E.   +8 more
europepmc   +1 more source

An intractable case of primary intra-axial central nervous system Rosai-Dorfman disease. [PDF]

Surg Neurol Int
Fujinaga A, Sadahiro H, Fujii N, Sugimoto K, Nomura S, Hoshii Y, Hirose T, Ishihara H.   +7 more
europepmc   +1 more source

Significance of adjuvant external beam radiotherapy of the orbit in managing uveal melanoma with extraocular extension. [PDF]

BMJ Open Ophthalmol
Düsberg NC, Bornfeld N, Merkel-Jens A, Rating P, Zeschnigk M, Sauerwein WAC, Stuschke M, Guberina M, Bechrakis NE, Biewald E.   +9 more
europepmc   +1 more source

Radioprotective Effect of Ascorbic Acid: A Need for Prophylactic Supplementation Pre- and Post-Radiation Exposure Among Patients and Healthcare Workers-A Perspective Article. [PDF]

Health Sci Rep
Mushemba J, Angolile CM, Kabuhaya JF, Mashauri HL.   +3 more
europepmc   +1 more source

Application of synthetic computed tomography based on a deep learning model in pelvic radiotherapy planning: A feasibility study. [PDF]

J Appl Clin Med Phys
Lin F, Hu J, Li Z, Wang J, Zhang W, Wen A, Li M, Hu Y, Wang Y.   +8 more
europepmc   +1 more source

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Dosage-rate in Radiotherapy

The British Journal of Radiology, 1944
Since this paper will be concerned mainly with experimental studies of the influence of dosage-rate on the response of isolated tissues, cells, and the component parts of cells, to ionizing radiations, it may be well to emphasise at the outset that the problem which presents itself to the radiotherapist wishing to make the best use of the time factor ...
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