Results 161 to 170 of about 25,142 (257)

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin   +10 more
wiley   +1 more source

Interfacial Synergy in a Band‐Aligned Low‐Dimensional Heterojunction Toward Broadband Photodetection

open access: yesAdvanced Science, EarlyView.
Monolithically integrating sensing and communication, a Ta2NiSe5/Sb2Te3 heterojunction achieves visible‐to‐near‐infrared photovoltaics with high‐speed terahertz photo‐thermoelectric detection at room temperature. By engineering a Type‐II van der Waals heterojunction, we overcome the intrinsic spectral limitations and disparate physical requirements of ...
Yuanfeng Wen   +20 more
wiley   +1 more source

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

open access: yesAdvanced Science, EarlyView.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang   +13 more
wiley   +1 more source

Pt Single‐Atom Activates Surface Lattice Oxygen for Enhanced Acetone Detection Mediated by the MvK Mechanism

open access: yesAdvanced Science, EarlyView.
A Pt single‐atom‐loaded CuO sensing material is developed for acetone detection, demonstrating remarkably enhanced sensing performance. The introduction of Pt single atoms effectively activates the lattice oxygen of the CuO support. A new sensing mechanism based on the Mars‐van Krevelen catalytic mechanism is proposed, offering new insights into the ...
Liang Zhao   +8 more
wiley   +1 more source

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

open access: yesAdvanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu   +6 more
wiley   +1 more source

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