Results 141 to 150 of about 89,757 (298)

Ion Concentration and Voltage Imaging With Fluorescent Nanodiamonds

Advanced Materials, EarlyView.
We demonstrate reversible switching between the fluorescent NV0 and the dark NV+ state, in sub‐30 nm FNDs via surface oxidation and hydrogenation, respectively. In an electrochemical cell, we show that the fluorescence from hydrogenated particles enables all‐optical imaging of voltages and ion concentrations at the micrometer scale.
Patrick Voorhoeve, Alessandro Mameli, Hiroshi Abe, Takeshi Ohshima, Qiang Sun, Anita Quigley, Rob Kapsa, Nikolai Dontschuk, Philipp Reineck   +8 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Iterative Selection of DNA Nanostructures for Cellular Uptake

Advanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar, Lisa Eichhorn, Jakub Palacka, Sandra Ly, Erik Benson   +4 more
wiley   +1 more source

Inductively Expandable Supraparticles as Microscopic Force Generators for Remote Mechanical Actuation

Advanced Materials, EarlyView.
This study demonstrates the combination of magnetic nanoparticles and functional blowing agents into supraparticles. Upon induction heating, they actuate via rapid gas generation or extensive volume expansion. These supraparticles lift up to 25 000 times their own mass and rapidly open cured epoxy resins, providing a versatile strategy for fast micron ...
Leoni Luthardt, Stephan Müssig, Robert Luxenhofer, Karl Mandel   +3 more
wiley   +1 more source

Inhaled siRNA therapy targeting RAGE for pulmonary inflammation: a first-in-human randomized trial. [PDF]

Nat Med
O'Carroll M, Kasahara D, Huetsch J, Reed T, Perkins TN, Zhou R, Moser L, Tomasini-Johansson B, Ta A, Oury TD, Pei T, Hamilton J, Bush EW, Leeper NJ, Salathe M, RAGE study consortium.   +15 more
europepmc   +1 more source

Dynamic Electrophoretic Assembly Coupled With Water‐Splitting‐Induced pH Control Enables Precision Ion Sieving Membranes

Advanced Materials, EarlyView.
A green, external‐catalyst‐free route grows defect‐free covalent organic framework membranes directly on ion‐exchange supports using an alternating electric field and in situ‐generated acid. Through a self‐regulating, self‐healing mechanism, the membranes achieve near‐complete, ultra‐fast separation of monovalent ions such as Li+, Na+, and K+, offering
Mohammad Hossein Jandaghian, Petric Marc Ruya, Ipek Ozyurt, Ali Atyabi, Samuel Eyley, Wim Thielemans, Alexander Volodin, Riccardo Alessandri, Xing Yang   +8 more
wiley   +1 more source

Insulin enhances RAGE ectodomain shedding by inducing Rab14-dependent ADAM10 cell surface trafficking in human aortic endothelial cells. [PDF]

PLoS One
Baek CH, Kim H, Moon SY, Lee EK, Yang WS.   +4 more
europepmc   +1 more source

Lithography‐Compatible Conductive Metal–Organic Frameworks for Scalable Electronics

Advanced Materials, EarlyView.
Conductive MOF thin films are integrated as gate electrodes in semiconductor devices through a photolithography‐compatible patterning strategy. CVD‐grown 2D MOF thin films enable stable operation across bottom‐gate MoS2/MoTe2 field‐effect transistors and top‐gate IGZO arrays, highlighting the potential of conductive MOFs as functional electronic ...
Hyeonwoo Lee, Han Joo Lee, Myeonggeun Choe, Jeehong Park, Yeonjin Yi, Seongil Im, Suk Hyun Park, Hee Cheul Choi, Ji Hoon Park, Sarah S. Park   +9 more
wiley   +1 more source

Decoding RAGE in diabetes: a pathogenic signaling hub modulated by decoy receptors in diabetic complications. [PDF]

Front Clin Diabetes Healthc
Srithongchai Y, Harashima A, Munesue S, Kimura K, Oshima Y, Tanaka M, Takahashi H, Sakulsak P, Uramoto C, Leerach N, Yamamoto Y.   +10 more
europepmc   +1 more source

D4.4 - Final Version of Game Applications for Scenario Pilots

, 2018
This final report provides an overview of the final versions of the RAGE games made using the RAGE assets after the first round of pilot testing and formative evaluation.
Saunter, Ian, Gaisbachgrabner, Kerstin, Platon, Thierry, Cook, Jeremy, Star, Kam, Wentworth, Felix, Westera, Wim, Piesk, Jens, Glass, Jaret, Spice, Ellis   +9 more
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